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1. WO2020139057 - COMPOSITION FOR PREVENTING AND TREATING MUSCLE DISEASE OR IMPROVING MUSCLE FUNCTION, COMPRISING ILLICIUM VERUM EXTRACT OR SHIKIMIC ACID

Publication Number WO/2020/139057
Publication Date 02.07.2020
International Application No. PCT/KR2019/018726
International Filing Date 30.12.2019
IPC
A61K 36/79 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
79Schisandraceae (Schisandra family)
A61K 31/191 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19Carboxylic acids, e.g. valproic acid
191Acyclic acids having two or more hydroxy groups, e.g. gluconic acid
A61P 21/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
21Drugs for disorders of the muscular or neuromuscular system
A23L 33/105 2016.01
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D91; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
33Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
10using additives
105Plant extracts, their artificial duplicates or their derivatives
A61K 8/9789 2017.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
96containing materials, or derivatives thereof, of undetermined constitution
97from algae, fungi, lichens or plants; from derivatives thereof
9783Angiosperms
9789Magnoliopsida
A61K 8/365 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
33containing oxygen
36Carboxylic acids; Salts or anhydrides thereof
365Hydroxycarboxylic acids; Ketocarboxylic acids
CPC
A61K 36/79
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
79Schisandraceae (Schisandra family)
Applicants
  • (주)앗코스텍 AAT COSTECH CO., LTD. [KR]/[KR]
Inventors
  • 황재관 HWANG, Jae Kwan
  • 김창희 KIM, Changhee
  • 유지희 YOO, Ji Hee
Agents
  • 특허법인 이룸리온 ERUUM & LEEON INTELLECTUAL PROPERTY LAW FIRM
Priority Data
10-2018-017273128.12.2018KR
10-2019-007667026.06.2019KR
Publication Language Korean (KO)
Filing Language Korean (KO)
Designated States
Title
(EN) COMPOSITION FOR PREVENTING AND TREATING MUSCLE DISEASE OR IMPROVING MUSCLE FUNCTION, COMPRISING ILLICIUM VERUM EXTRACT OR SHIKIMIC ACID
(FR) COMPOSITION POUR PRÉVENIR ET TRAITER UNE MALADIE MUSCULAIRE OU AMÉLIORER LA FONCTION MUSCULAIRE, COMPRENANT UN EXTRAIT D'ILLICIUM VERUM OU DE L'ACIDE SHIKIMIQUE
(KO) 팔각회향 추출물 또는 시킴산을 함유하는 근육 질환 예방 및 치료용 또는 근 기능 개선용 조성물
Abstract
(EN)
The present invention relates to a composition for preventing and treating a muscle disease or improving muscle function, comprising an Illicium verum extract and shikimic acid. The Illicium verum extract and shikimic acid according to the present invention have the effect of increasing activity of mTOR involved in muscle protein synthesis and reducing the mRNA expression of MuRF-1 and atrogin-1 involved in muscle protein degradation, and increase muscle mass and enhance muscle function, thereby being useful for preventing, treating, or alleviating various muscle diseases such as atony, muscular atrophy, muscular dystrophy, muscular degeneration, myasthenia, cachexia, and sarcopenia.
(FR)
La présente invention concerne une composition permettant de prévenir et de traiter une maladie musculaire ou d'améliorer la fonction musculaire, comprenant un extrait d'Illicium verum et de l'acide shikimique. L'extrait d'Illicium verum et l'acide shikimique selon la présente invention ont pour effet d'augmenter l'activité mTOR impliquée dans la synthèse de protéines musculaires et de réduire l'expression d'ARNm de MuRF-1 et d'atrogine-1 impliquées dans la dégradation des protéines musculaires, et d'augmenter la masse musculaire et d'améliorer la fonction musculaire, ce qui est utile pour prévenir, traiter ou soulager diverses maladies musculaires telles que l'atonie, l'atrophie musculaire, la dystrophie musculaire, la dégénérescence musculaire, la myasthénie, la cachexie et la sarcopénie.
(KO)
본 발명은 팔각회향 추출물 및 시킴산을 함유하는 근육 질환 예방 및 치료용 또는 근 기능 개선용 조성물에 관한 것이다. 본 발명에 따른 팔각회향 추출물 및 시킴산은 근 단백질 합성에 관여하는 mTOR의 활성 증가 및 근 단백질 분해에 관여하는 MuRF-1과 atrogin-1의 mRNA 발현을 감소시키는 효과가 있으며, 근육량을 증가시키고 및 근기능을 향상시켜, 긴장감퇴증(atony), 근위축증(muscular atrophy), 근이영양증(muscular dystrophy), 근육 퇴화, 근무력증, 악액질(cachexia) 및 근육감소증(sarcopenia) 등의 각종 근육 질환 예방, 치료 또는 개선에 유용하게 이용될 수 있다.
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Latest bibliographic data on file with the International Bureau