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1. WO2020138912 - PHARMACEUTICAL COMPOSITION COMPRISING PIBF PROTEIN AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF INFLAMMATORY DISEASE

Publication Number WO/2020/138912
Publication Date 02.07.2020
International Application No. PCT/KR2019/018394
International Filing Date 24.12.2019
IPC
A61K 38/16 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
A61K 45/06 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61P 29/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents; Non-steroidal antiinflammatory drugs (NSAIDs)
A23L 33/17 2016.01
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D91; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
33Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
10using additives
17Amino acids, peptides or proteins
CPC
A23L 33/17
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A23B - A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT
33Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
10using additives
17Amino acids, peptides or proteins
A61K 38/16
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
A61K 45/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61K 47/68
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
50the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
51the non-active ingredient being a modifying agent
68the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
A61P 11/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
06Antiasthmatics
A61P 29/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29Non-central analgesic, antipyretic or anti-inflammatory agents, e.g antirheumatic agents; Non-steroidal anti-inflammatory drugs (NSAIDs)
Applicants
  • 울산대학교 산학협력단 UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION [KR]/[KR]
  • 재단법인 아산사회복지재단 THE ASAN FOUNDATION [KR]/[KR]
Inventors
  • 조유숙 CHO, You Sook
  • 최준표 CHOI, Jun Pyo
  • 백인정 BAEK, In Jeoung
  • 권혁수 KWON, Hyouk Soo
  • 박소영 PARK, So Young
Agents
  • 특허법인 이룸리온 ERUUM & LEEON INTELLECTUAL PROPERTY LAW FIRM
Priority Data
10-2018-017289728.12.2018KR
Publication Language Korean (KO)
Filing Language Korean (KO)
Designated States
Title
(EN) PHARMACEUTICAL COMPOSITION COMPRISING PIBF PROTEIN AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF INFLAMMATORY DISEASE
(FR) COMPOSITION PHARMACEUTIQUE COMPRENANT UNE PROTÉINE PIBF EN TANT QUE PRINCIPE ACTIF POUR LA PRÉVENTION OU LE TRAITEMENT D'UNE MALADIE INFLAMMATOIRE
(KO) PIBF 단백질을 유효성분으로 함유하는 염증성 질환 예방 또는 치료용 약학 조성물
Abstract
(EN)
The present invention relates to a pharmaceutical composition comprising a progesterone induced blocking factor (PIBF) protein as an active ingredient for prevention or treatment of inflammatory disease. In the present invention, menopausal asthma animal models have been experimentally identified to decrease airway inflammation when treated with PIBF protein. Thus, the composition can be advantageously used in menopausal female asthma patients.
(FR)
La présente invention concerne une composition pharmaceutique comprenant une protéine de facteur de blocage induit par la progestérone (PIBF) en tant que principe actif pour la prévention ou le traitement d'une maladie inflammatoire. Dans la présente invention, des modèles animaux de l'asthme ménopausique ont été identifiés expérimentalement pour réduire l'inflammation des voies respiratoires lorsqu'ils sont traités avec la protéine PIBF. Ainsi, la composition peut être avantageusement utilisée chez des patientes ménopausées souffrant d'asthme.
(KO)
본 발명은 PIBF (progesterone induced blocking factor) 단백질을 유효성분으로 함유하는 염증성 질환 예방 또는 치료용 약학 조성물에 관한 것이다. 본 발명은, 폐경 후 천식 동물 모델에, PIBF 단백질을 처리하여 기도 염증 감소를 실험적으로 확인하였는 바, 폐경 후 여성 천식 환자들에게 유용하게 사용할 수 있다.
Also published as
Latest bibliographic data on file with the International Bureau