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1. WO2020138266 - COMPOSITION FOR SUPRESSING SECRETION OF EXTRACELLULAR VESICLES

Publication Number WO/2020/138266
Publication Date 02.07.2020
International Application No. PCT/JP2019/051079
International Filing Date 26.12.2019
IPC
A61P 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
A61P 35/04 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
04specific for metastasis
A61P 43/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43Drugs for specific purposes, not provided for in groups A61P1/-A61P41/108
C12N 5/02 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
02Propagation of single cells or cells in suspension; Maintenance thereof; Culture media therefor
A61K 31/404 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
40having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
403condensed with carbocyclic rings, e.g. carbazole
404Indoles, e.g. pindolol
A61K 31/409 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
40having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
409having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
CPC
A61K 31/404
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
40having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
403condensed with carbocyclic rings, e.g. carbazole
404Indoles, e.g. pindolol
A61K 31/409
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
40having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
409having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
A61K 31/555
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
555containing heavy metals, e.g. hemin, hematin, melarsoprol
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
A61P 35/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
04specific for metastasis
A61P 43/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applicants
  • 日産化学株式会社 NISSAN CHEMICAL CORPORATION [JP]/[JP]
  • 国立大学法人金沢大学 NATIONAL UNIVERSITY CORPORATION KANAZAWA UNIVERSITY [JP]/[JP]
Inventors
  • 的場 一隆 MATOBA Kazutaka
  • 木田 克彦 KIDA Katsuhiko
  • 西野 泰斗 NISHINO Taito
  • 華山 力成 HANAYAMA Rikinari
  • 吉田 孟史 YOSHIDA Takeshi
Agents
  • 特許業務法人 津国 TSUKUNI & ASSOCIATES
  • 山村 大介 YAMAMURA Daisuke
Priority Data
2018-24501527.12.2018JP
Publication Language Japanese (JA)
Filing Language Japanese (JA)
Designated States
Title
(EN) COMPOSITION FOR SUPRESSING SECRETION OF EXTRACELLULAR VESICLES
(FR) COMPOSITION PERMETTANT DE SUPPRIMER LA SÉCRÉTION DE VÉSICULES EXTRACELLULAIRES
(JA) 細胞外小胞の分泌を抑制するための組成物
Abstract
(EN)
A composition for supressing the secretion of extacellular vesicles is provided. A composition for supressing the secretion of extracellular vesicles, said composition containing a compound having the structure of formula II (each substituent in the formula is as defined in the specification) or a pharmaceutically acceptable salt thereof, or a compound having the structure of formula I (each substituent in the formula is as defined in the specification) or a metal complex or pharmaceutically acceptable salt thereof.
(FR)
L'invention porte sur une composition permettant de supprimer la sécrétion de vésicules extracellulaires. Une composition permettant de supprimer la sécrétion de vésicules extracellulaires, ladite composition contenant un composé ayant la structure de formule II (chaque substituant dans la formule étant tel que défini dans la description) ou un sel pharmaceutiquement acceptable de ce dernier, ou un composé ayant la structure de formule I (chaque substituant dans la formule étant tel que défini dans la description) ou un complexe métallique ou un sel pharmaceutiquement acceptable de ce dernier.
(JA)
細胞外小胞の分泌を抑制するための組成物を提供すること。 細胞外小胞の分泌を抑制するための組成物であって、式II(式中、各置換基は、明細書に定義されるとおりである)の構造を有する化合物、又はその薬学的に許容し得る塩、或いは式I(式中、各置換基は、明細書に定義されるとおりである)の構造を有する化合物、若しくはその金属錯体、又はその薬学的に許容し得る塩を含む、組成物。
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