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1. WO2020137880 - OXYTOCIN DERIVATIVE AND USE THEREOF

Publication Number WO/2020/137880
Publication Date 02.07.2020
International Application No. PCT/JP2019/050089
International Filing Date 20.12.2019
Chapter 2 Demand Filed 07.08.2020
IPC
A61P 15/04 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
15Drugs for genital or sexual disorders; Contraceptives
04for inducing labour or abortion; Uterotonics
A61P 25/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
A61P 25/18 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
A61P 43/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43Drugs for specific purposes, not provided for in groups A61P1/-A61P41/108
C07K 7/16 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
7Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04Linear peptides containing only normal peptide links
16Oxytocins; Vasopressins; Related peptides
C07K 7/54 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
7Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
50Cyclic peptides containing at least one abnormal peptide link
54with at least one abnormal peptide link in the ring
CPC
A61K 38/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
12Cyclic peptides ; , e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
A61P 15/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
15Drugs for genital or sexual disorders
04for inducing labour or abortion; Uterotonics
A61P 25/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
A61P 25/18
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
A61P 43/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
C07K 7/16
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
7Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04Linear peptides containing only normal peptide links
16Oxytocins; Vasopressins; Related peptides
Applicants
  • 国立大学法人北海道大学 NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY [JP]/[JP]
Inventors
  • 東田 陽博 HIGASHIDA Haruhiro
  • 横山 茂 YOKOYAMA Shigeru
  • チェレパノフ スタニスラフ ミハイロヴィチ CHEREPANOV Stanislav Mikhaylovich
  • 周東 智 SHUTO Satoshi
  • 一ノ瀬 亘 ICHINOSE Wataru
Agents
  • 西澤 和純 NISHIZAWA Kazuyoshi
  • 伊藤 英輔 ITO Eisuke
  • 春田 洋孝 HARUTA Hirotaka
Priority Data
2018-24614127.12.2018JP
Publication Language Japanese (JA)
Filing Language Japanese (JA)
Designated States
Title
(EN) OXYTOCIN DERIVATIVE AND USE THEREOF
(FR) DÉRIVÉ D'OXYTOCINE ET SON UTILISATION
(JA) オキシトシン誘導体及びその使用
Abstract
(EN)
The present invention is a compound represented by Formula (1), a pharmaceutically acceptable salt thereof, or a solvate thereof (in Formula (1), X is a sulfur atom or a methylene group and R3 is a group represented by Formula (2) or Formula (3)).
(FR)
La présente invention concerne un composé représenté par la Formule (1), un sel pharmaceutiquement acceptable de celui-ci, ou un solvate de celui-ci (dans la formule (1), X représente un atome de soufre ou un groupe méthylène et R3 représente un groupe représenté par la formule (2) ou la formule (3)).
(JA)
下記式(1)で表される化合物若しくはその薬理学的に許容される塩又はそれらの溶媒和物(下記式(1)中、Xは硫黄原子又はメチレン基であり、Rは下記式(2)又は下記式(3)で表される基である。)。
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