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1. WO2020136191 - PEPTIDE ANALOGUE OF THYMULIN (PAT) FOR USE IN THE TREATMENT OF STROKES

Publication Number WO/2020/136191
Publication Date 02.07.2020
International Application No. PCT/EP2019/087004
International Filing Date 24.12.2019
IPC
A61K 38/08 2019.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
08Peptides having 5 to 11 amino acids
A61P 9/10 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9Drugs for disorders of the cardiovascular system
10for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
A61P 25/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
CPC
A61K 38/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
08Peptides having 5 to 11 amino acids
Applicants
  • ORPHIT [FR]/[FR]
Inventors
  • LARUELLE, Stéphane
Agents
  • AXE PI
Priority Data
187433128.12.2018FR
Publication Language French (FR)
Filing Language French (FR)
Designated States
Title
(EN) PEPTIDE ANALOGUE OF THYMULIN (PAT) FOR USE IN THE TREATMENT OF STROKES
(FR) PEPTIDE ANALOGUE DE LA THYMULINE (PAT) POUR SON UTILISATION DANS LE TRAITEMENT DES ACCIDENTS VASCULAIRES CEREBRAUX
Abstract
(EN)
The invention relates to the prevention and/or treatment of strokes. The invention is characterised in that a peptide analogue of thymulin (PAT) corresponding to the following sequence: SEQ ID n°1: Glu-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asp (EAKSQGGSD), or one of the pharmaceutically acceptable salts thereof, is used in the prevention and/or treatment of strokes. The invention also relates to a composition comprising such a peptide which is used according to the invention and dissolved in an appropriate solvent, optionally accompanied by a preservative, buffering agent, isotonicity adjuvant or surfactant, alone or in combination.
(FR)
L'invention concerne la prévention et/ou le traitement des accidents vasculaires cérébraux. L'invention se caractérise en ce qu'un peptide analogue de la thymuline (PAT) correspondant à la séquence suivante : SEQ ID n°1 : Glu-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asp (EAKSQGGSD), ou un de ses sels pharmaceutiquement acceptables, est utilisé dans la prévention et/ou le traitement des accidents vasculaires cérébraux. L'invention concerne enfin une composition comprenant un tel peptide utilisé selon l'invention, dissous dans un solvant approprié, éventuellement accompagné de conservateur, agent tampon, adjuvant d'isotonicité, agent tensioactif pris seul ou en mélange.
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Latest bibliographic data on file with the International Bureau