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1. WO2020135401 - TREATMENT USE OF PYRROLOPYRIMIDINE COMPOUND, AND SOLID PHARMACEUTICAL COMPOSITION OF PYRROLOPYRIMIDINE COMPOUND

Publication Number WO/2020/135401
Publication Date 02.07.2020
International Application No. PCT/CN2019/127837
International Filing Date 24.12.2019
IPC
C07D 487/04 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
487Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
A61K 31/519 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
519ortho- or peri-condensed with heterocyclic rings
A61K 9/20 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
20Pills, lozenges or tablets
A61P 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
CPC
A61K 31/519
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two ; or more; nitrogen atoms as the only ring heteroatoms, e.g. piperazine ; or tetrazines
505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
519ortho- or peri-condensed with heterocyclic rings
A61K 9/20
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
20Pills, tablets, ; discs, rods
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
C07D 487/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
487Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
Applicants
  • 正大天晴药业集团股份有限公司 CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. [CN]/[CN]
  • 连云港润众制药有限公司 LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD. [CN]/[CN]
  • 首药控股(北京)有限公司 SHOUYAO HOLDINGS (BEIJING) CO., LTD. [CN]/[CN]
Inventors
  • 王栋 WANG, Dong
  • 李清侠 LI, Qingxia
  • 戴峻 DAI, Jun
  • 李晨 LI, Chen
  • 江竹莲 JIANG, Zhulian
  • 孙艳清 SUN, Yanqing
  • 陈晶晶 CHEN, Jingjing
  • 金玲玲 JIN, Lingling
  • 刘君动 LIU, Jundong
  • 李其德 LI, Qide
Agents
  • 北京英赛嘉华知识产权代理有限责任公司 INSIGHT INTELLECTUAL PROPERTY LIMITED
Priority Data
201811581815.824.12.2018CN
201910679429.026.07.2019CN
Publication Language Chinese (ZH)
Filing Language Chinese (ZH)
Designated States
Title
(EN) TREATMENT USE OF PYRROLOPYRIMIDINE COMPOUND, AND SOLID PHARMACEUTICAL COMPOSITION OF PYRROLOPYRIMIDINE COMPOUND
(FR) UTILISATION THÉRAPEUTIQUE DE COMPOSÉ DE PYRROLOPYRIMIDINE, ET COMPOSITION PHARMACEUTIQUE SOLIDE DE COMPOSÉ DE PYRROLOPYRIMIDINE
(ZH) 吡咯并嘧啶化合物的治疗用途及其固体药物组合物
Abstract
(EN)
A treatment use of a pyrrolopyrimidine compound, and a solid pharmaceutical composition of a pyrrolopyrimidine compound. In particular, the present invention relates to a pyrrolopyrimidine compound or a pharmaceutical composition thereof for treating myeloproliferative neoplasms, and a method therefor or a use thereof.
(FR)
L'invention concerne une utilisation thérapeutique d'un composé de pyrrolopyrimidine, et une composition pharmaceutique solide d'un composé de pyrrolopyrimidine. En particulier, la présente invention concerne un composé de pyrrolopyrimidine ou une composition pharmaceutique associée pour le traitement de néoplasmes myéloprolifératifs, et un procédé s'y rapportant ou leur utilisation.
(ZH)
一种吡咯并嘧啶化合物的治疗用途及其固体药物组合物。具体涉及用于治疗骨髓增殖性肿瘤的吡咯并嘧啶化合物或其药物组合物,吡咯并嘧啶化合物或其药物组合物用于治疗骨髓增殖性肿瘤的方法或用途。
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