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1. WO2020118238 - QUATERNARY AMMONIUM SALTS AS INHIBITORS OF TRIMETHYLAMINE PRODUCTION

Publication Number WO/2020/118238
Publication Date 11.06.2020
International Application No. PCT/US2019/065045
International Filing Date 06.12.2019
IPC
G06F 19/16 2011.01
GPHYSICS
06COMPUTING; CALCULATING OR COUNTING
FELECTRIC DIGITAL DATA PROCESSING
19Digital computing or data processing equipment or methods, specially adapted for specific applications
10Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology
16for molecular structure, e.g. structure alignment, structural or functional relations, protein folding, domain topologies, drug targeting using structure data, involving two-dimensional or three-dimensional structures
G06F 19/12 2011.01
GPHYSICS
06COMPUTING; CALCULATING OR COUNTING
FELECTRIC DIGITAL DATA PROCESSING
19Digital computing or data processing equipment or methods, specially adapted for specific applications
10Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology
12for modelling or simulation in systems biology, e.g. probabilistic or dynamic models, gene-regulatory networks, protein interaction networks or metabolic networks
Applicants
  • KINTAI THERAPEUTICS, INC. [US]/[US]
Inventors
  • NUDEL, Kathleen
  • LIU, Jenny
  • BRIGGS, Timothy
  • GUNASEKERA, Dinara Shashanka
  • MARTINEZ-DEL CAMPO, Ana
  • BOGART, Elijah
  • TAYLOR, Steven
  • PROUDFOOT, John
  • ROSS, Cheri
  • TEFFERA, Yohannes
  • YASUDA, Koji
  • DOUD, Devin Forest Reed
  • BILLINGS, Gabriel
  • PECK, Spencer Cory
  • LAFRANCE, Danny
  • AJAYI, Kehinde
Agents
  • MACALPINE, Jill K.
Priority Data
62/776,45906.12.2018US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) QUATERNARY AMMONIUM SALTS AS INHIBITORS OF TRIMETHYLAMINE PRODUCTION
(FR) SELS D'AMMONIUM QUATERNAIRE EN TANT QU'INHIBITEURS DE LA PRODUCTION DE TRIMÉTHYLAMINE
Abstract
(EN)
Provided are compounds that can inhibit pathogenic, bacterial metabolite production and conjugates of the same. Also provided are pharmaceutical compositions comprising the same and methods of using the same.
(FR)
L'invention concerne des composés qui peuvent inhiber la production de métabolites bactériens pathogènes et des conjugués associés. L'invention concerne également des compositions pharmaceutiques comprenant ces composés et leurs procédés d'utilisation.
Latest bibliographic data on file with the International Bureau