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1. WO2020117938 - PRODRUGS OF ANTI-CANCER AND ANTI-AUTOIMMUNE DISEASES THERAPEUTIC AGENTS, AND METHODS OF MAKING AND USE THEREOF

Publication Number WO/2020/117938
Publication Date 11.06.2020
International Application No. PCT/US2019/064471
International Filing Date 04.12.2019
IPC
A61K 31/513 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
513having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
C07D 239/54 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
239Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
02not condensed with other rings
24having three or more double bonds between ring members or between ring members and non-ring members
28with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
46Two or more oxygen, sulfur or nitrogen atoms
52Two oxygen atoms
54as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
Applicants
  • UNIVERSITY OF MARYLAND, BALTIMORE [US]/[US]
Inventors
  • XUE, Fengtian
  • SHU, Yan
  • AI, Yong
Agents
  • GHIDU, Victor, P.
  • BEARDELL, Louis, W.
  • DAVIS, Kenneth, J.
  • CHAI, Deping
  • CAO, Ping
Priority Data
62/774,99304.12.2018US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) PRODRUGS OF ANTI-CANCER AND ANTI-AUTOIMMUNE DISEASES THERAPEUTIC AGENTS, AND METHODS OF MAKING AND USE THEREOF
(FR) PROMÉDICAMENTS D'AGENTS THÉRAPEUTIQUES CONTRE LE CANCER ET LES MALADIES AUTO-IMMUNES, ET LEURS PROCÉDÉS DE PRODUCTION ET D'UTILISATION
Abstract
(EN)
The invention relates to prodrugs of anti-cancer and anti-autoimmune diseases therapeutic agents, and methods of making and use thereof.
(FR)
L'invention concerne des promédicaments d'agents thérapeutiques contre le cancer et les maladies auto-immunes, ainsi que leurs procédés de production et d'utilisation.
Latest bibliographic data on file with the International Bureau