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1. WO2020117590 - HIV VACCINE IMMUNOGENS

Publication Number WO/2020/117590
Publication Date 11.06.2020
International Application No. PCT/US2019/063619
International Filing Date 27.11.2019
IPC
C07K 14/005 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005from viruses
C07K 14/15 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005from viruses
08RNA viruses
15Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus, human T-cell leukaemia-lymphoma virus
C07K 14/155 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005from viruses
08RNA viruses
15Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus, human T-cell leukaemia-lymphoma virus
155Lentiviridae, e.g. human immunodeficiency virus (HIV), visna-maedi virus, equine infectious anaemia virus
CPC
A61K 39/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
C07K 14/005
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005from viruses
C12N 2740/16023
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2740Reverse Transcribing RNA Viruses
00011Reverse Transcribing RNA Viruses
10011Retroviridae
16011Human Immunodeficiency Virus, HIV
16023Virus like particles [VLP]
C12N 2740/16134
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2740Reverse Transcribing RNA Viruses
00011Reverse Transcribing RNA Viruses
10011Retroviridae
16011Human Immunodeficiency Virus, HIV
16111concerning HIV env
16134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Applicants
  • THE ROCKEFELLER UNIVERSITY [US]/[US]
  • CALIFORNIA INSTITUTE OF TECHNOLOGY [US]/[US]
Inventors
  • NUSSENZWEIG, Michel
  • BJORKMAN, Pamela, J.
  • ESCOLANO, Amelia
  • GRISTICK, Harry
Agents
  • NORTON, Gerard, P.
  • BARRISON, Flynn
  • BUTCH III, Peter, J.
  • HALPERN, Nancy, E.
  • CHEN, Joe
Priority Data
62/775,19204.12.2018US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) HIV VACCINE IMMUNOGENS
(FR) IMMUNOGÈNES DE VACCIN CONTRE LE VIH
Abstract
(EN)
This disclosure provides HIV immunogens and use thereof for generating an immune response in a subject. Also disclosed is a method of isolating anti-HIV antibodies and use thereof. This disclosure further provides a method for treating or preventing a human immunodeficiency type 1 (HIV-1) infection in a subject using the disclosed HIV immunogens and/or antibodies.
(FR)
La présente invention concerne des immunogènes contre le VIH et leur utilisation pour produire une réponse immunitaire chez un sujet. L'invention concerne également une méthode d'isolement d'anticorps anti-VIH et leur utilisation. La présente invention concerne en outre une méthode pour traiter ou prévenir une infection par le virus de l'immunodéficience humaine de type 1 (VIH-1) chez un sujet faisant appel aux immunogènes et/ou aux anticorps contre le VIH selon l'invention.
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