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1. WO2020117368 - COMPRESSION AND HEAT-ASSISTED PRODUCTION OF SILK-BASED MATERIALS

Publication Number WO/2020/117368
Publication Date 11.06.2020
International Application No. PCT/US2019/055736
International Filing Date 10.10.2019
IPC
A61K 47/42 2017.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
B32B 9/02 2006.01
BPERFORMING OPERATIONS; TRANSPORTING
32LAYERED PRODUCTS
BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
9Layered products essentially comprising a particular substance not covered by groups B32B11/-B32B29/137
02comprising animal or vegetable substances
C08L 89/00 2006.01
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
89Compositions of proteins; Compositions of derivatives thereof
CPC
A61L 27/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27Materials for ; grafts or; prostheses or for coating ; grafts or; prostheses
B32B 9/02
BPERFORMING OPERATIONS; TRANSPORTING
32LAYERED PRODUCTS
BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
9Layered products comprising a particular substance not covered by groups B32B11/00 - B32B29/00
02comprising animal or vegetable substances ; , e.g. cork, bamboo, starch
C08J 5/00
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G
5Manufacture of articles or shaped materials containing macromolecular substances
C08L 89/00
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
89Compositions of proteins; Compositions of derivatives thereof
D06M 10/10
DTEXTILES; PAPER
06TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
MTREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
10Physical treatment of fibres, threads, yarns, fabrics, or fibrous goods made from such materials, e.g. ultrasonic, corona discharge, irradiation, electric currents, or magnetic fields; Physical treatment combined with treatment with chemical compounds or elements
04Physical treatment combined with treatment with chemical compounds or elements
08Organic compounds
10Macromolecular compounds
Applicants
  • TRUSTEES OF TUFTS COLLEGE [US]/[US]
Inventors
  • KAPLAN, David, L.
  • OMENETTO, Fiorenzo, G.
  • LI, Chunmei
  • GUO, Chengchen
Agents
  • SCHLEICHER, James, M.
Priority Data
62/743,97510.10.2018US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) COMPRESSION AND HEAT-ASSISTED PRODUCTION OF SILK-BASED MATERIALS
(FR) PRODUCTION ASSISTÉE PAR COMPRESSION ET CHALEUR DE MATIÈRES À BASE DE SOIE
Abstract
(EN)
In some embodiments, the present disclosure provides methods including the steps of (i) providing silk fibroin material comprising substantially amorphous structure, and (ii) applying at least one of elevated temperature and elevated pressure to the silk fibroin material to form a silk fibroin article, wherein the applying induces fusion between at least a portion of the silk fibroin and structural change of fibroin in the silk fibroin material. In some embodiments, the present disclosure also provides silk fibroin articles made in accordance with the methods disclosed herein.
(FR)
Dans certains modes de réalisation, la présente divulgation concerne des procédés comprenant les étapes consistant à (i) fournir un matière de fibroïne de soie comprenant une structure sensiblement amorphe, et (ii) appliquer au moins une température élevée et une pression élevée sur la matière de fibroïne de soie pour former un article en fibroïne de soie, l'application induisant la fusion entre au moins une partie de la fibroïne de soie et le changement structural de la fibroïne dans la matière de fibroïne de soie. Dans certains modes de réalisation, la présente divulgation concerne également des articles en fibroïne de soie fabriqués selon les procédés divulgués.
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