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1. WO2020117360 - FORMULATION FOR USE IN TREATING OSTEOARTHRITIS

Publication Number WO/2020/117360
Publication Date 11.06.2020
International Application No. PCT/US2019/053657
International Filing Date 27.09.2019
IPC
A61B 1/317 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
1Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
313for introducing through surgical openings, e.g. laparoscopes
317for bones or joints, e.g. osteoscopes, arthroscopes
A61B 5/05 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
05Measuring for diagnosis by means of electric currents or magnetic fields
A61B 17/56 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
17Surgical instruments, devices or methods, e.g. tourniquets
56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
A61K 38/16 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
A61K 38/17 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17from animals; from humans
C07K 14/47 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
Applicants
  • ORTHOTROPHIX, INC.
Inventors
  • KUMAGAI, Yoshinari
  • MCGUIRE, Dawn
  • MILLER, Meghan
  • ROSEN, David
Agents
  • BOZICEVIC, Karl
Priority Data
62/755,05604.12.2018US
62/787,88103.01.2019US
62/811,36627.02.2019US
62/838,71225.04.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) FORMULATION FOR USE IN TREATING OSTEOARTHRITIS
(FR) FORMULATION POUR UTILISATION DANS LE TRAITEMENT DE L’ARTHROSE
Abstract
(EN)
A formulation for use in treating osteoarthritis by modifying the shape change of bone(s) underlying articular cartilage is disclosed. The use comprises evaluating the bone shape of the patient's joint, injecting the patient with a peptide of SEQ ID No. 1 or applying other therapeutic interventions that can reduce the shape change of the bone(s) underlying articular cartilage, and thereafter evaluating the bone shape of the patient's joint.
(FR)
La présente invention concerne une formulation pour une utilisation dans le traitement de l’arthrose par modification du changement de forme de cartilage articulaire sous-jacent à un ou plusieurs os. L’utilisation comprend l’évaluation de la forme osseuse de l’articulation du patient, l’injection au patient d’un peptide de SEQ ID N° 1 ou l’application d’autres interventions thérapeutiques qui peuvent réduire le changement de forme du cartilage articulaire sous-jacent à un ou plusieurs os, puis l’évaluation de la forme osseuse de l’articulation du patient.
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