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1. WO2020116733 - NOVEL LACTOBACILLUS REUTERI ATG-F4 STRAIN HAVING FUNCTION OF ENHANCING DOPAMINE SECRETION AND PHARMACEUTICAL COMPOSITION COMPRISING SAME FOR PREVENTION OR TREATMENT OF PSYCHOPATHY

Publication Number WO/2020/116733
Publication Date 11.06.2020
International Application No. PCT/KR2019/006937
International Filing Date 10.06.2019
IPC
C12N 1/20 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
1Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
20Bacteria; Culture media therefor
A23L 33/135 2016.01
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D91; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
33Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
10using additives
135Bacteria or derivatives thereof, e.g. probiotics
A61K 35/747
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
66Microorganisms or materials therefrom
74Bacteria
741Probiotics
744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
747Lactobacilli, e.g. L. acidophilus or L. brevis
A61P 25/18 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
C12R 1/225 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C-C12Q75
1Microorganisms
01Bacteria or actinomycetales
225Lactobacillus
CPC
A23L 33/135
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A23B - A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT
33Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
10using additives
135Bacteria or derivatives thereof, e.g. probiotics
A23V 2002/00
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES
2002Food compositions, function of food ingredients or processes for food or foodstuffs
A23V 2200/322
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES
2200Function of food ingredients
30Foods, ingredients or supplements having a functional effect on health
322having an effect on the health of the nervous system or on mental function
A23Y 2220/71
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
YINDEXING SCHEME RELATING TO LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
2220Lactobacillus
71Reuteri
A61K 35/747
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
66Microorganisms or materials therefrom
74Bacteria
741Probiotics
744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
747Lactobacilli, e.g. L. acidophilus or L. brevis
A61P 25/18
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
Applicants
  • (주) 에이투젠 ATOGEN CO., LTD [KR]/[KR]
Inventors
  • 백보람 BECK, Bo Ram
  • 강지희 KANG, Ji Hee
  • 박건석 PARK, Gun Seok
  • 임성훈 IM, Sung Hoon
  • 정도윤 JEONG, Do Yeun
  • 이용현 LEE, Yong Hyun
Agents
  • 특허법인오암 OAM PATENT & TRADEMARK LAW FIRM
Priority Data
10-2018-015705507.12.2018KR
Publication Language Korean (KO)
Filing Language Korean (KO)
Designated States
Title
(EN) NOVEL LACTOBACILLUS REUTERI ATG-F4 STRAIN HAVING FUNCTION OF ENHANCING DOPAMINE SECRETION AND PHARMACEUTICAL COMPOSITION COMPRISING SAME FOR PREVENTION OR TREATMENT OF PSYCHOPATHY
(FR) NOUVELLE SOUCHE ATG-F4 DE LACTOBACILLUS REUTERI POSSÉDANT UNE FONCTION D'AMÉLIORATION DE LA SÉCRÉTION DE DOPAMINE ET COMPOSITION PHARMACEUTIQUE LA COMPRENANT POUR LA PRÉVENTION OU LE TRAITEMENT DE LA PSYCHOPATHIE
(KO) 도파민 분비 증진 기능이 있는 신규한 락토바실러스 루테리 ATG-F4 균주, 이를 함유하는 정신질환의 예방 또는 치료용 조성물
Abstract
(EN)
The present invention relates to a Lactobacillus reuteri ATG-F4 strain (accession number KCTC13717BP). Having the function of enhancing dopamine secretion, the strain is available in a pharmaceutical composition or health functional food for prevention or alleviation of psychopathy, such as memory impairment, depressive disorder, generalized anxiety disorder, bipolar disorder, etc., and Parkinson's disease, or in a composition very effective for improving memory or cognitive function. Furthermore, the strain exhibits the anti-inflammatory efficacy of upregulating the expression of Interleukin-10 (IL-10) and suppressing the generation of nitric oxide (NO) and is free of resistance to antibacterial agents and as such, can be readily applied to various foods that have health improvement effects.
(FR)
La présente invention concerne une souche de Lactobacillus reuteri ATG-F4 (numéro de dépôt KCTC13717BP). Ayant pour fonction d'améliorer la sécrétion de dopamine, la souche est disponible dans une composition pharmaceutique ou un aliment fonctionnel de santé pour la prévention ou le soulagement de la psychopathie, telle que la déficience de la mémoire, un trouble dépressif, un trouble anxieux généralisé, un trouble bipolaire, etc, et la maladie de Parkinson, ou dans une composition très efficace pour améliorer la mémoire ou la fonction cognitive. En outre, la souche présente l'efficacité anti-inflammatoire de la régulation à la hausse de l'expression de l'interleukine-10 (IL-10) et la suppression de la génération d'oxyde nitrique (NO), est exempte de résistance à des agents antibactériens et, en tant que tel, peut être facilement appliquée à divers aliments ayant des effets d'amélioration de la santé.
(KO)
본 발명은 락토바실러스 루테리 ATG-F4 균주(수탁번호 KCTC13717BP)에 관한 것으로서, 상기 균주는 도파민 분비 증진 기능이 있어 기억장애, 우울장애, 범불안장애, 양극성장애 등의 정신질환, 파킨슨병 등을 예방 또는 개선할 수 있는 약학 조성물이나 건강기능식품으로 이용가능하며, 기억력이나 인지기능의 개선에도 매우 효과적인 조성물로 사용될 수 있다. 게다가 상기 균주는 IL-10(Interleukin-10)의 발현을 증가시키며, NO(Nitric Oxide)의 생성을 억제하는 항염 효능이 있는 데다가 항생제에 대한 내성이 없어 각종 건강증진 효능이 있는 식품에 용이하게 적용가능하다.
Also published as
Latest bibliographic data on file with the International Bureau