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1. WO2020116537 - RNAI MOLECULE FOR TREATING CANCER

Publication Number WO/2020/116537
Publication Date 11.06.2020
International Application No. PCT/JP2019/047505
International Filing Date 04.12.2019
IPC
A61K 31/713 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
7088Compounds having three or more nucleosides or nucleotides
713Double-stranded nucleic acids or oligonucleotides
A61K 48/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
A61P 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
A61P 35/02 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
02specific for leukemia
C12N 15/113 2010.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
11DNA or RNA fragments; Modified forms thereof
113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
Applicants
  • 日東電工株式会社 NITTO DENKO CORPORATION [JP]/[JP]
Inventors
  • 田中 洋行 TANAKA Hiroyuki
  • 味呑 憲二郎 MINOMI Kenjiro
  • 高橋 博一 TAKAHASHI Hirokazu
  • 田村 保明 TAMURA Yasuaki
  • 武井 則雄 TAKEI Norio
  • 米田 明弘 YONEDA Akihiro
Agents
  • 小林 浩 KOBAYASHI Hiroshi
  • 三橋 規樹 MITSUHASHI Motoki
  • 鈴木 康仁 SUZUKI Yasuhito
Priority Data
2018-22828405.12.2018JP
Publication Language Japanese (JA)
Filing Language Japanese (JA)
Designated States
Title
(EN) RNAI MOLECULE FOR TREATING CANCER
(FR) MOLÉCULE D'ARNI POUR LE TRAITEMENT DU CANCER
(JA) がん処置用RNAi分子
Abstract
(EN)
The present invention pertains to an RNAi molecule that is for treating cancer and that includes the antisense strand of a nucleotide sequence of SEQ ID NO: 1, and a method for treating cancer, the method comprising administering an effective dose of the RNAi molecule to a subject in need of same.
(FR)
La présente invention concerne une molécule d'ARNi qui est destinée au traitement du cancer et qui comprend le brin antisens d'une séquence nucléotidique de SEQ ID NO : 1, ainsi qu'une méthode de traitement du cancer, la méthode comprenant l'administration d'une dose efficace de la molécule d'ARNi au patient qui en a besoin.
(JA)
本発明は、配列番号1のヌクレオチド配列をアンチセンス鎖に含む、がん処置用RNAi分子、有効量の前記RNAi分子を、それを必要とする対象に投与することを含む、がんを処置する方法に関する。
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