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1. WO2020115709 - MODIFIED RELEASE PHARMACEUTICAL COMPOSITION

Publication Number WO/2020/115709
Publication Date 11.06.2020
International Application No. PCT/IB2019/060497
International Filing Date 05.12.2019
IPC
A61K 9/20 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
20Pills, lozenges or tablets
A61K 31/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
CPC
A61K 31/4458
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non condensed pyridines; Hydrogenated derivatives thereof
445Non condensed piperidines, e.g. piperocaine
4458only substituted in position 2, e.g. methylphenidate
A61K 9/2013
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
20Pills, tablets, ; discs, rods
2004Excipients; Inactive ingredients
2013Organic compounds, e.g. phospholipids, fats
A61K 9/2018
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
20Pills, tablets, ; discs, rods
2004Excipients; Inactive ingredients
2013Organic compounds, e.g. phospholipids, fats
2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
A61K 9/2027
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
20Pills, tablets, ; discs, rods
2004Excipients; Inactive ingredients
2022Organic macromolecular compounds
2027obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
A61K 9/2054
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
20Pills, tablets, ; discs, rods
2004Excipients; Inactive ingredients
2022Organic macromolecular compounds
205Polysaccharides, e.g. alginate, gums; Cyclodextrin
2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
A61K 9/2068
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
20Pills, tablets, ; discs, rods
2004Excipients; Inactive ingredients
2068Compounds of unknown constitution, e.g. material from plants or animals
Applicants
  • FLAMEL IRELAND LIMITED [IE]/[IE]
Inventors
  • NONY, Guillaume
  • GUILLARD, Hervé
  • POULIQUEN, Gauthier
  • CONSOLA, Sabrina
Priority Data
62/776,30106.12.2018US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) MODIFIED RELEASE PHARMACEUTICAL COMPOSITION
(FR) COMPOSITION PHARMACEUTIQUE À LIBÉRATION MODIFIÉE
Abstract
(EN)
Pharmaceutical compositions that include a bi-modal, mutiparticulate mixtures of immediate release particles and modified release particles to provide a therapeutic effect of methylphenidate, dexmethylphenidate, structural analogs of methylphenidate or dexmethylphenidate, pharmaceutical salts thereof, and mixtures thereof overextended periods of time.
(FR)
L'invention concerne des compositions pharmaceutiques comprenant un mélange bimodal et mutiparticulaire de particules à libération immédiate et de particules à libération modifiée pour fournir un effet thérapeutique du méthylphénidate, du dexméthylphénidate, des analogues structuraux du méthylphénidate ou du dexméthylphénidate, des sels pharmaceutiques de celui-ci et des mélanges de ceux-ci sur des périodes prolongées.
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