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1. WO2020115648 - VACCINE FOR THE PREVENTION AND TREATMENT OF C. DIFFICILE INFECTIONS AND THE USE THEREOF

Publication Number WO/2020/115648
Publication Date 11.06.2020
International Application No. PCT/IB2019/060389
International Filing Date 03.12.2019
IPC
A61K 39/08 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
02Bacterial antigens
08Clostridium, e.g. Clostridium tetani
A61K 39/39 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
39characterised by the immunostimulating additives, e.g. chemical adjuvants
A61K 39/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
CPC
A61K 2039/54
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
54characterised by the route of administration
A61K 2039/541
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
54characterised by the route of administration
541Mucosal route
A61K 2039/55505
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
555characterised by a specific combination antigen/adjuvant
55505Inorganic adjuvants
A61K 2039/55555
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
555characterised by a specific combination antigen/adjuvant
55511Organic adjuvants
55555Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
A61K 39/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
02Bacterial antigens
08Clostridium, e.g. Clostridium tetani
A61K 39/39
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
39characterised by the immunostimulating additives, e.g. chemical adjuvants
Applicants
  • INSTYTUT IMMUNOLOGII I TERAPII DOŚWIADCZALNEJ IM. LUDWIKA HIRSZFELDA POLSKIEJ AKADEMII NAUK [PL]/[PL]
Inventors
  • MYC, Andrzej
  • RAZIM, Agnieszka
  • GÓRSKA, Sabina
  • GAMIAN, Andrzej
Agents
  • GODLEWSKI, Piotr
Priority Data
P.42804504.12.2018PL
Publication Language English (EN)
Filing Language Polish (PL)
Designated States
Title
(EN) VACCINE FOR THE PREVENTION AND TREATMENT OF C. DIFFICILE INFECTIONS AND THE USE THEREOF
(FR) VACCIN POUR LA PRÉVENTION ET LE TRAITEMENT D'INFECTIONS PAR C. DIFFICILE ET SON UTILISATION
Abstract
(EN)
The present invention relates to a veterinary vaccine containing nanoadjuvants in the form of emulsion and Clostridium difficile antigens, as well as the use of the vaccine in the preventions and treatment of a C. difficile infection, especially in birds and mammals. The object of the invention is also the use of this vaccine to produce C. difficile-specific antibodies.
(FR)
La présente invention concerne un vaccin vétérinaire contenant des nanoadjuvants sous la forme d'une émulsion et d'antigènes de Clostridium difficile, ainsi que l'utilisation du vaccin dans les préventions et le traitement d'une infection par C. difficile, en particulier chez les oiseaux et les mammifères. L'invention concerne également l'utilisation de ce vaccin pour produire des anticorps spécifiques de C. difficile.
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