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1. WO2020115570 - METHOD FOR MAKING COATED SILICONE HYDROGEL CONTACT LENSES

Publication Number WO/2020/115570
Publication Date 11.06.2020
International Application No. PCT/IB2019/054496
International Filing Date 30.05.2019
IPC
B29D 11/00 2006.01
BPERFORMING OPERATIONS; TRANSPORTING
29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
DPRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
11Producing optical elements, e.g. lenses or prisms
CPC
B29D 11/00038
BPERFORMING OPERATIONS; TRANSPORTING
29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
DPRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
11Producing optical elements, e.g. lenses or prisms
00009Production of simple or compound lenses
00038Production of contact lenses
B29D 11/0025
BPERFORMING OPERATIONS; TRANSPORTING
29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
DPRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
11Producing optical elements, e.g. lenses or prisms
00009Production of simple or compound lenses
00038Production of contact lenses
00125Auxiliary operations, e.g. removing oxygen from the mould, conveying moulds from a storage to the production line in an inert atmosphere
0025Removing impurities from contact lenses, e.g. leaching
B29D 11/00865
BPERFORMING OPERATIONS; TRANSPORTING
29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
DPRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
11Producing optical elements, e.g. lenses or prisms
00865Applying coatings; tinting; colouring
B29D 11/00923
BPERFORMING OPERATIONS; TRANSPORTING
29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
DPRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
11Producing optical elements, e.g. lenses or prisms
00865Applying coatings; tinting; colouring
00923on lens surfaces for colouring or tinting
B29K 2683/00
BPERFORMING OPERATIONS; TRANSPORTING
29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
KINDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR ; MOULDS, ; REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
2683Use of polymers having silicon, with or without sulfur, nitrogen, oxygen or carbon only, in the main chain, for preformed parts, e.g. for inserts
C08F 290/068
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
290Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
02on to polymers modified by introduction of unsaturated end groups
06Polymers provided for in subclass C08G
068Polysiloxanes
Applicants
  • ALCON INC. [CH]/[CH]
Inventors
  • QIU, Yongxing
  • CHIANG, Chung-Yuan
  • SAMUEL, Newton T.
  • GOVAN, Richard
  • DAUENHAUER, Ciara
Priority Data
62/774,44103.12.2018US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHOD FOR MAKING COATED SILICONE HYDROGEL CONTACT LENSES
(FR) PROCÉDÉ DE FABRICATION DE LENTILLES DE CONTACT EN SILICONE HYDROGEL ENROBÉES
Abstract
(EN)
The invention is generally related to a method for producing coated silicone hydrogel contact lenses each of which has a hydrogel coating thereon and a relative high resistance to uptakes of polycationic antimicrobials as characterized by having a polyquaternium-1-uptake of less than 0.40 micrograms/lens. The hydrogel coating is formed by covalently attached a hydrophilic polymeric material onto a base coating of a polyanionic polymer on a SiHy contact lens. In this method, lower polyquaternium-1-uptake is achieved by using a rinse solution with a higher pH and/or a higher ionic strength (higher salt concentration) for rinsing a treated silicone hydrogel contact lens with a base coating of polyanionic polymer.
(FR)
La présente invention concerne, d'une manière générale, un procédé de fabrication de lentilles de contact en silicone hydrogel enrobées dont chacune est recouverte d'un revêtement d'hydrogel et présente une résistance élevée relative à l'absorption d'agents antimicrobiens polycationiques, caractérisée en ce qu'elle présente une absorption de polyquaternium-1 inférieure à 0,40 microgramme/lentille. Le revêtement d'hydrogel est formé par liaison covalente d'un matériau polymère hydrophile sur un revêtement de base d'un polymère polyanionique sur une lentille de contact SiHy. Dans ce procédé, une absorption de polyquaternium-1 inférieure est obtenue en utilisant une solution de rinçage ayant un pH plus élevé et/ou une force ionique supérieure (concentration en sel plus élevée) pour rincer une lentille de contact de silicone hydrogel traitée avec un revêtement de base de polymère polyanionique.
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