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1. WO2020115368 - METHOD FOR DETERMINING PATIENT'S RESPONSIVENESS TO TYPE I INTERFERON TREATMENT AND USE OF TYPE I INTERFERON TO TREAT PATIENT HAVING SPECIFIED SINGLE NUCLEOTIDE POLYMORPHISM

Publication Number WO/2020/115368
Publication Date 11.06.2020
International Application No. PCT/FI2019/050870
International Filing Date 04.12.2019
IPC
C12Q 1/6883 2018.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
6883for diseases caused by alterations of genetic material
CPC
C12Q 1/6883
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
68involving nucleic acids
6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
6883for diseases caused by alterations of genetic material
C12Q 2600/156
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
2600Oligonucleotides characterized by their use
156Polymorphic or mutational markers
Applicants
  • FARON PHARMACEUTICALS OY [FI]/[FI]
Inventors
  • JALKANEN, Juho
  • JALKANEN, Markku
  • KARVONEN, Matti
Agents
  • BERGGREN OY
Priority Data
2018604104.12.2018FI
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHOD FOR DETERMINING PATIENT'S RESPONSIVENESS TO TYPE I INTERFERON TREATMENT AND USE OF TYPE I INTERFERON TO TREAT PATIENT HAVING SPECIFIED SINGLE NUCLEOTIDE POLYMORPHISM
(FR) PROCÉDÉ POUR DÉTERMINER LA RÉACTIVITÉ CHEZ UN PATIENT À UN TRAITEMENT PAR INTERFÉRON DE TYPE 1 ET UTILISATION D'INTERFÉRON DE TYPE 1 POUR TRAITER UN PATIENT AYANT UN POLYMORPHISME MONONUCLÉOTIDIQUE SPÉCIFIÉ
Abstract
(EN)
A method for determining a patient's responsiveness to a therapy comprising administration of type I interferon in order to make the decision to treat a patient with type I interferon and use of a SNP rs9984273 (C/T) in IFNAR2 as a marker for determining patients' responsiveness to said therapy.
(FR)
L'invention concerne également un procédé pour déterminer la réactivité chez un patient à une thérapie comprenant l'administration d'interféron de type 1 afin de prendre la décision de traiter un patient par interféron de type 1 et l'utilisation d'un polymorphisme mononucléotidique (SNP) rs9984273 (C/T) dans l'IFNAR2 en tant que marqueur pour déterminer la réactivité chez les patients à ladite thérapie.
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