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1. WO2020115329 - A RECOMBINANT KOI HERPESVIRUS (KHV) AND A DIVA VACCINE FOR PREVENTING AND/OR TREATING A DISEASE CAUSED BY KHV

Publication Number WO/2020/115329
Publication Date 11.06.2020
International Application No. PCT/EP2019/084249
International Filing Date 09.12.2019
IPC
A61K 39/12 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
CPC
A61K 2039/5254
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
51comprising whole cells, viruses or DNA/RNA
525Virus
5254avirulent or attenuated
A61K 2039/552
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
55characterised by the host/recipient, e.g. newborn with maternal antibodies
552Veterinary vaccine
A61K 39/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
C12N 2710/16021
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2710dsDNA Viruses
00011dsDNA Viruses
16011Herpesviridae
16021Viruses as such, e.g. new isolates, mutants or their genomic sequences
C12N 2710/16022
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2710dsDNA Viruses
00011dsDNA Viruses
16011Herpesviridae
16022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
C12N 2710/16034
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2710dsDNA Viruses
00011dsDNA Viruses
16011Herpesviridae
16034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Applicants
  • IDT BIOLOGIKA GMBH [DE]/[DE]
Inventors
  • FUCHS, Walter
  • SCHROEDER, Lars
  • BERGMANN, Sven M.
  • KLAFACK, Sandro
  • FICHTNER, Dieter
  • DAUBER, Malte
  • LEE, Pei-Yu Alison
Agents
  • ISARPATENT - PATENT- UND RECHTSANWÄLTE BEHNISCH BARTH CHARLES HASSA PECKMANN UND PARTNER MBB
Priority Data
18211090.807.12.2018EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) A RECOMBINANT KOI HERPESVIRUS (KHV) AND A DIVA VACCINE FOR PREVENTING AND/OR TREATING A DISEASE CAUSED BY KHV
(FR) HERPESVIRUS CYHV3 (KHV) RECOMBINANT ET VACCIN DE TYPE DIVA POUR PRÉVENIR ET/OU TRAITER UNE MALADIE PROVOQUÉE PAR LE KHV
Abstract
(EN)
The present invention relates to a recombinant KHV with a deficient ORF148/149, a recombinant KHV DNA encoding said KHV, a DIVA vaccine comprising said KHV and/or said DNA for preventing and/or treating disease caused by KHV in fish, such as Cyprinus carpio, a eukaryotic cell comprising said KHV and/or said DNA, a fish, such as Cyprinus carpio, vaccinated with said vaccine, and a method for preparing infectious particles of said KHV.
(FR)
La présente invention concerne un KHV recombinant avec un ORF148/149 déficient, un ADN de KHV recombinant codant pour ledit KHV, un vaccin de type DIVA comportant ledit KHV et/ou ledit ADN, destiné à prévenir et/ou à traiter une maladie provoquée par le KHV chez les poissons tels que Cyprinus carpio, une cellule eucaryote comportant ledit KHV et/ou ledit ADN, un poisson tel que Cyprinus carpio vacciné par ledit vaccin, et un procédé de préparation de particules infectieuses dudit KHV.
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