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1. WO2020115124 - FUNCTIONALIZED ENZYME-POWERED NANOMOTORS

Publication Number WO/2020/115124
Publication Date 11.06.2020
International Application No. PCT/EP2019/083662
International Filing Date 04.12.2019
IPC
B82B 1/00 2006.01
BPERFORMING OPERATIONS; TRANSPORTING
82NANOTECHNOLOGY
BNANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS, MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES AS DISCRETE UNITS; MANUFACTURE OR TREATMENT THEREOF
1Nanostructures formed by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
CPC
B82B 1/008
BPERFORMING OPERATIONS; TRANSPORTING
82NANOTECHNOLOGY
BNANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS, MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES AS DISCRETE UNITS; MANUFACTURE OR TREATMENT THEREOF
1Nanostructures formed by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
008Nanostructures not provided for in groups B82B1/001 - B82B1/007
B82Y 5/00
BPERFORMING OPERATIONS; TRANSPORTING
82NANOTECHNOLOGY
YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
5Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Applicants
  • FUNDACIÓ INSTITUT DE BIOENGINYERIA DE CATALUNYA [ES]/[ES]
  • INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS [ES]/[ES]
Inventors
  • SÁNCHEZ ORDÓÑEZ, Samuel
  • PATIÑO PADIAL, Tania
  • LOPES HORTELÃO, Ana Candida
Agents
  • ZBM PATENTS - ZEA, BARLOCCI & MARKVARDSEN
Priority Data
18382896.105.12.2018EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) FUNCTIONALIZED ENZYME-POWERED NANOMOTORS
(FR) NANOMOTEURS ALIMENTÉS PAR FONCTIONNALISATION ENZYMATIQUE
Abstract
(EN)
The present invention provides an enzyme-powered nanomotor,comprisinga particle with a surface,anenzyme,anda heterologous molecule; characterized in that the enzyme and the heterologous molecule are discontinuously attached over the whole surface of the particle. The invention also provides the nanomotor for use in therapy, diagnosis and prognosis, in particular, for the treatment of cancer.Additionally, the invention provides the use of the nanomotor for detecting an analyte in an isolated sample.
(FR)
La présente invention concerne un nanomoteur alimenté par fonctionnalisation enzymatique comprenant une particule ayant une surface, une enzyme et une molécule hétérologue; caractérisé en ce que l'enzyme et la molécule hétérologue sont fixées de manière discontinue sur toute la surface de la particule. L'invention concerne également le nanomoteur destiné à être utilisé dans la thérapie, le diagnostic et le pronostic, en particulier, pour le traitement du cancer. L'invention concerne également l'utilisation du nanomoteur pour détecter un analyte dans un échantillon isolé.
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