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International application No. Applicant's or agent's file reference
PCT/EP2019/083441 219142aa/iva
International filing date (day/month/year) (Earliest) Priority Date (day/month/year)
03 December 2019 04 December 2018
FOR FURTHER ACTION: See Form PCT/ISA/220 as well as, where applicable, item 5 below.
This international search report has been prepared by this International Searching Authority and is transmitted to the applicant according to Article 18. A copy is being transmitted to the International Bureau.
It is also accompanied by a copy of each prior art document cited in this report.
1. Basis of the report
a. With regard to the language, the international search was carried out on the basis of:
the international application in the language in which it was filed.
a translation of the international application into                                          which is the language of a translation furnished for the purposes of international search (Rules 12.3(a) and 23.1(b)).
This international search report has been established taking into account the rectification of an obvious mistake authorized by or notified to this Authority under Rule 91 (Rule 43.6bis(a)).
With regard to any nucleotide and/or amino acid sequence disclosed in the international application, the international search was carried out on the basis of a sequence listing:
2. Certain claims were found unsearchable
3. Unity of invention is lacking
4. Title of the invention
The text is approved as submitted by the applicant.
The text has been established by this Authority to read as follows:
5. Abstract
The text is approved as submitted by the applicant.
The text has been established, according to Rule 38.2, by this Authority as it appears in Box No. IV. The applicant may, within one month from the date of mailing of this international search report, submit comments to this Authority.
6. Drawings
The figure of the drawings to be published with the abstract is Figure No.     3    
as suggested by the applicant.
as selected by this Authority, because the applicant failed to suggest a figure.
as selected by this Authority, because this figure better characterizes the invention.
none of the figures is to be published with the abstract.


     A61M 15/00 (2006.01)i; A61M 16/00 (2006.01)i; A61M 11/00 (2006.01)i; A61M 16/10 (2006.01)i
According to International Patent Classification (IPC) or to both national classification and IPC


Minimum documentation searched (classification system followed by classification symbols):
Documentation searched other than minimum documentation to the extent that such documents are included in the fields searched:
Electronic data base consulted during the international search (name of data base and, where practicable, search terms used):
EPO-Internal, WPI Data


Category* Citation of document, with indication, where appropriate, of the relevant passages Relevant to claim No.
EP 1868570 B1 (AEROGEN INC [US]) 20 September 2017 (2017-09-20)
cited in the application
figures 4, 9
paragraphs [0054], [0051], [0052], [0055], [0072]
US 5603314 A (BONO MICHAEL [US]) 18 February 1997 (1997-02-18)
abstract; figure 3
column 3, line 47 - column 6, line 59
US 6116233 A (DENYER JONATHAN STANLEY HAROLD [GB] ET AL) 12 September 2000 (2000-09-12)
abstract; figure 5
column 2, line 66 - column 3, line 13
EP 1927373 A1 (PARI PHARMA GMBH) 04 June 2008 (2008-06-04)
abstract; figure 1
paragraphs [0024] - [0034]
Special categories of cited documents:
document defining the general state of the art which is not considered to be of particular relevance
document cited by the applicant in the international application
earlier application or patent but published on or after the international filing date
document which may throw doubts on priority claim(s) or which is cited to establish the publication date of another citation or other special reason (as specified)
document referring to an oral disclosure, use, exhibition or other means
document published prior to the international filing date but later than the priority date claimed
later document published after the international filing date or priority date and not in conflict with the application but cited to understand the principle or theory underlying the invention
document of particular relevance; the claimed invention cannot be considered novel or cannot be considered to involve an inventive step when the document is taken alone
document of particular relevance; the claimed invention cannot be considered to involve an inventive step when the document is combined with one or more other such documents, such combination being obvious to a person skilled in the art
document member of the same patent family


Patent document cited in search report Publication date
Patent family member(s) Publication date
EP 1868570 B1
20 September 2017
AU 2006227168 A1
BR PI0609725 A2
CA 2599018 A1
CN 101146517 A
EP 1868570 A2
ES 2642041 T3
IL 186162 A
JP 5008093 B2
JP 2008536546 A
KR 20070113257 A
NZ 561943 A
NZ 595112 A
US 2005217666 A1
US 2008142002 A1
WO 2006102345 A2
28 September 2006
20 April 2010
28 September 2006
19 March 2008
26 December 2007
15 November 2017
31 May 2016
22 August 2012
11 September 2008
28 November 2007
30 July 2010
28 March 2013
06 October 2005
19 June 2008
28 September 2006
US 5603314 A
18 February 1997
US 5603314 A
US 5611332 A
US 5630409 A
18 February 1997
18 March 1997
20 May 1997
US 6116233 A
12 September 2000
AT 160093 T
AU 699149 B2
AU 4730093 A
CA 2105945 A1
DE 69315147 D1
DE 69315147 T2
DK 0587380 T3
EP 0587380 A1
GB 2273660 A
HK 1002140 A1
JP 3503071 B2
JP H06190044 A
NZ 248600 A
US 6116233 A
15 November 1997
26 November 1998
17 March 1994
12 March 1994
18 December 1997
10 June 1998
27 July 1998
16 March 1994
29 June 1994
31 July 1998
02 March 2004
12 July 1994
26 March 1996
12 September 2000
EP 1927373 A1
04 June 2008
EP 1927373 A1
US 2008299049 A1
04 June 2008
04 December 2008
Name and mailing address of the ISA/:
European Patent Office
P.B. 5818, Patentlaan 2, 2280 HV Rijswijk,
Telephone No. (+31-70)340-2040
Facsimile No. (+31-70)340-3016
Date of the actual completion of the international search:
09 January 2020
Date of mailing of the international search report:
22 January 2020
Authorized officer:
Moraru, Liviu
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