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1. WO2020114853 - PRODRUGS OF 4-((1R,3S)-6-CHLORO-3-PHENYL-2,3-DIHYDRO-1H-INDEN-1-YL)-1,2,2-TRIMETHYLPIPERAZINE AND 4-((1/R,3S)-6-CHLORO-3-(PHENYL-D5)-2,3-DIHYDRO-1H-INDEN-1-YL)-2,2-DIMETHY-1-(METHYL-D3)PIPERAZINE


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INTERNATIONAL SEARCH REPORT (ISR)
Part 1:  1  2  3  4  5  6          Part 2:  A  B  C  D  E 
International application No. Applicant's or agent's file reference
PCT/EP2019/082715 1128-WO-PCT
International filing date (day/month/year) (Earliest) Priority Date (day/month/year)
27 November 2019 03 December 2018
Applicant
H. LUNDBECK A/S
FOR FURTHER ACTION: See Form PCT/ISA/220 as well as, where applicable, item 5 below.
This international search report has been prepared by this International Searching Authority and is transmitted to the applicant according to Article 18. A copy is being transmitted to the International Bureau.
It is also accompanied by a copy of each prior art document cited in this report.
1. Basis of the report
a. With regard to the language, the international search was carried out on the basis of:
the international application in the language in which it was filed.
a translation of the international application into                                          which is the language of a translation furnished for the purposes of international search (Rules 12.3(a) and 23.1(b)).
b.
This international search report has been established taking into account the rectification of an obvious mistake authorized by or notified to this Authority under Rule 91 (Rule 43.6bis(a)).
c.
With regard to any nucleotide and/or amino acid sequence disclosed in the international application, the international search was carried out on the basis of a sequence listing:
2. Certain claims were found unsearchable
3. Unity of invention is lacking
4. Title of the invention
The text is approved as submitted by the applicant.
The text has been established by this Authority to read as follows:
5. Abstract
The text is approved as submitted by the applicant.
The text has been established, according to Rule 38.2, by this Authority as it appears in Box No. IV. The applicant may, within one month from the date of mailing of this international search report, submit comments to this Authority.
6. Drawings
a.
The figure of the drawings to be published with the abstract is Figure No. ____________
as suggested by the applicant.
as selected by this Authority, because the applicant failed to suggest a figure.
as selected by this Authority, because this figure better characterizes the invention.
b.
none of the figures is to be published with the abstract.

A. CLASSIFICATION OF SUBJECT MATTER

     C07D 295/037 (2006.01)i; A61P 25/18 (2006.01)i; A61K 31/495 (2006.01)i
According to International Patent Classification (IPC) or to both national classification and IPC

B. FIELDS SEARCHED

Minimum documentation searched (classification system followed by classification symbols):
     C07D; A61P; A61K
Documentation searched other than minimum documentation to the extent that such documents are included in the fields searched:
Electronic data base consulted during the international search (name of data base and, where practicable, search terms used):
EPO-Internal, CHEM ABS Data

C. DOCUMENTS CONSIDERED TO BE RELEVANT

Category* Citation of document, with indication, where appropriate, of the relevant passages Relevant to claim No.
(1)
A
WO 9210192 A1 (LUNDBECK & CO AS H [DK]) 25 June 1992 (1992-06-25)
1-10
claims 1-10
(2)
A
WO 2005016901 A1 (LUNDBECK & CO AS H [DK]; BANG-ANDERSEN BENNY [DK] ET AL.) 24 February 2005 (2005-02-24)
1-10
claims 1-33
*
Special categories of cited documents:
"A"
document defining the general state of the art which is not considered to be of particular relevance
"D"
document cited by the applicant in the international application
"E"
earlier application or patent but published on or after the international filing date
"L"
document which may throw doubts on priority claim(s) or which is cited to establish the publication date of another citation or other special reason (as specified)
"O"
document referring to an oral disclosure, use, exhibition or other means
"P"
document published prior to the international filing date but later than the priority date claimed
"T"
later document published after the international filing date or priority date and not in conflict with the application but cited to understand the principle or theory underlying the invention
"X"
document of particular relevance; the claimed invention cannot be considered novel or cannot be considered to involve an inventive step when the document is taken alone
"Y"
document of particular relevance; the claimed invention cannot be considered to involve an inventive step when the document is combined with one or more other such documents, such combination being obvious to a person skilled in the art
"&"
document member of the same patent family

D. INFORMATION ON PATENT FAMILY MEMBERS

Patent document cited in search report Publication date
(day/month/year)
Patent family member(s) Publication date
(day/month/year)
WO 9210192 A1
25 June 1992
AT 121294 T
AU 653375 B2
CA 2097715 A1
DE 69109132 D1
DE 69109132 T2
DK 0560868 T3
EP 0560868 A1
ES 2071479 T3
FI 932541 A
HK 122995 A
IE 914076 A1
IL 100164 A
JP 3245418 B2
JP H06503073 A
KR 930702980 A
NO 179947 B
NZ 240734 A
PT 99673 A
WO 9210192 A1
ZA 9109563 B
15 May 1995
29 September 1994
05 June 1992
24 May 1995
31 August 1995
02 October 1995
22 September 1993
16 June 1995
23 July 1993
04 August 1995
17 June 1992
18 June 1996
15 January 2002
07 April 1994
29 November 1993
07 October 1996
25 February 1994
30 October 1992
25 June 1992
26 August 1992
WO 2005016901 A1
24 February 2005
AU 2004265021 A1
AU 2004265022 A1
AU 2010206058 A1
BR PI0413555 A
BR PI0413595 A
CA 2536073 A1
CA 2536144 A1
CY 1113039 T1
EP 1658276 A1
EP 1658277 A1
HR P20120389 T1
HR P20121010 T1
IL 173788 A
IS 8265 A
JP 5043429 B2
JP 5144930 B2
JP 5553802 B2
JP 2007502783 A
JP 2007502784 A
JP 2011201924 A
MX PA06001838 A
MX PA06001938 A
NO 332048 B1
NZ 544715 A
NZ 575575 A
PL 1658277 T3
US 2006281758 A1
US 2006281759 A1
US 2010324291 A1
US 2011053957 A1
WO 2005016900 A1
WO 2005016901 A1
24 February 2005
24 February 2005
19 August 2010
17 October 2006
17 October 2006
24 February 2005
24 February 2005
13 April 2016
24 May 2006
24 May 2006
30 June 2012
31 January 2013
31 January 2013
26 January 2006
10 October 2012
13 February 2013
16 July 2014
15 February 2007
15 February 2007
13 October 2011
04 May 2006
17 May 2006
11 June 2012
25 September 2009
30 April 2010
31 October 2012
14 December 2006
14 December 2006
23 December 2010
03 March 2011
24 February 2005
24 February 2005
Name and mailing address of the ISA/:
European Patent Office
P.B. 5818, Patentlaan 2, 2280 HV Rijswijk,
Netherlands
Telephone No. (+31-70)340-2040
Facsimile No. (+31-70)340-3016
Date of the actual completion of the international search:
12 February 2020
Date of mailing of the international search report:
25 February 2020
Authorized officer:
Kleidernigg, Oliver
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