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1. WO2020114615 - BISPECIFIC ANTIBODIES BINDING FACTOR IXA AND FACTOR X

Publication Number WO/2020/114615
Publication Date 11.06.2020
International Application No. PCT/EP2018/084038
International Filing Date 07.12.2018
IPC
C07K 16/36 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
36against blood coagulation factors
A61P 7/02 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
7Drugs for disorders of the blood or the extracellular fluid
02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
CPC
A61P 7/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
7Drugs for disorders of the blood or the extracellular fluid
02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
C07K 16/36
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
36against blood coagulation factors
C07K 2317/75
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2317Immunoglobulins specific features
70characterized by effect upon binding to a cell or to an antigen
75Agonist effect on antigen
C07K 2317/92
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2317Immunoglobulins specific features
90characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Applicants
  • BAXALTA GMBH [CH]/[CH]
  • BAXALTA INCORPORATED [US]/[US]
  • NOVIMMUNE SA [CH]/[CH]
Inventors
  • DOCKAL, Michael
  • FISCHER, Nicolas
Agents
  • HOFFMANN EITLE PATENT- UND RECHTSANWÄLTE PARTMBB
Priority Data
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) BISPECIFIC ANTIBODIES BINDING FACTOR IXA AND FACTOR X
(FR) ANTICORPS BISPÉCIFIQUES SE LIANT AU FACTEUR IXA ET AU FACTEUR X
Abstract
(EN)
The present invention provides bispecific antibodies that bind to Factor IXa and Factor X and that have a procoagulant activity.
(FR)
La présente invention concerne des anticorps bispécifiques qui se lient au facteur IXa et au facteur X et qui ont une activité procoagulante.
Latest bibliographic data on file with the International Bureau