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1. WO2020114518 - TUMOR COMBINED IMMUNOTHERAPY

Publication Number WO/2020/114518
Publication Date 11.06.2020
International Application No. PCT/CN2019/124066
International Filing Date 09.12.2019
IPC
A61P 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
A61K 35/12 2015.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
A61K 31/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
Applicants
  • 科济生物医药(上海)有限公司 CARSGEN THERAPEUTICS CO., LTD. [CN]/[CN]
  • 上海市肿瘤研究所 SHANGHAI CANCER INSTITUTE [CN]/[CN]
Inventors
  • 李宗海 LI, Zonghai
  • 孙蕊心 SUN, Ruixin
Agents
  • 北京彩和律师事务所 BEIJING CAI HE LAW FIRM
Priority Data
201811497155.507.12.2018CN
Publication Language Chinese (ZH)
Filing Language Chinese (ZH)
Designated States
Title
(EN) TUMOR COMBINED IMMUNOTHERAPY
(FR) POLYIMMUNOTHÉRAPIE ANTI-TUMORALE
(ZH) 肿瘤联合免疫治疗
Abstract
(EN)
Provided is a method for tumor treatment, comprising administering immune effector cells and a PARP inhibitor to an individual suffering from a tumor, the immune effector cells expressing a receptor for identifying a tumor antigen. Further provided is a kit for tumor treatment.
(FR)
L'invention concerne une méthode de traitement d'une tumeur, consistant à administrer des cellules effectrices immunitaires et un inhibiteur de PARP à un individu souffrant d'une tumeur, les cellules effectrices immunitaires exprimant un récepteur permettant d'identifier un antigène tumoral. L'invention concerne en outre un kit pour le traitement d'une tumeur.
(ZH)
提供了一种治疗肿瘤的方法,包括对患有肿瘤的个体施用免疫效应细胞和PARP抑制剂,所述免疫效应细胞表达有识别肿瘤抗原的受体。还提供了一种用于治疗肿瘤的试剂盒。
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