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1. WO2020114444 - USE OF DIACEREIN IN PREPARATION OF ANTIVIRAL DRUGS AND TREATMENT OF VIRUS INFECTIONS

Publication Number WO/2020/114444
Publication Date 11.06.2020
International Application No. PCT/CN2019/123209
International Filing Date 05.12.2019
IPC
A61K 31/222 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
21Esters, e.g. nitroglycerine, selenocyanates
215of carboxylic acids
22of acyclic acids, e.g. pravastatin
222with compounds having aromatic groups, e.g. dipivefrine, ibopamine
A61K 31/192 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19Carboxylic acids, e.g. valproic acid
192having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
A61K 31/122 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
12Ketones
122having the oxygen atom directly attached to a ring, e.g. quinones, vitamin K1, anthralin
A61P 31/12 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
Applicants
  • 中检科医药科技(北京)集团有限公司 CHINA INSPECTION SCIENCE PHARMACEUTICAL (BEIJING) GROUP CO., LTD [CN]/[CN]
Inventors
  • 朱水芳 ZHU, Shuifang
  • 丛浩龙 CONG, Haolong
  • 王晨光 WANG, Chenguang
  • 田志清 TIAN, Zhiqing
  • 姜帆 JIANG, Fan
Agents
  • 北京海虹嘉诚知识产权代理有限公司 HAIHONG JIACHENG INTELLECTUAL PROPERTY & PARTNERS
Priority Data
201811479088.405.12.2018CN
201811486556.006.12.2018CN
201811502639.410.12.2018CN
Publication Language Chinese (ZH)
Filing Language Chinese (ZH)
Designated States
Title
(EN) USE OF DIACEREIN IN PREPARATION OF ANTIVIRAL DRUGS AND TREATMENT OF VIRUS INFECTIONS
(FR) UTILISATION DE DIACÉRÉINE DANS LA PRÉPARATION DE MÉDICAMENTS ANTIVIRAUX ET TRAITEMENT D'INFECTIONS VIRALES
(ZH) 双醋瑞因在制备抗病毒药物及治疗病毒感染中的用途
Abstract
(EN)
Pharmaceutical use of diacerein. Experiments show that diacerein can effectively inhibit hepadnavirus, retrovirus, enterovirus, orthomyxovirus, filovirus, reovirus, arenavirus, hepatitis E virus, astrovirus, orbivirus, coronavirus, parvovirus, adenovirus, polyomavirus, herpes virus, poxvirus, human papilloma virus, paramyxovirus, flavivirus, alphavirus, and rhabdovirus.
(FR)
L'invention concerne une utilisation pharmaceutique de la diacéréine. Des expériences ont révélé que de la diacéréine pouvait inhiber efficacement les hépadnavirus, les rétrovirus, les entérovirus, les orthomyxovirus, les filovirus, les réovirus, les arénavirus, le virus de l'hépatite E, les astrovirus, les orbivirus, les coronavirus, les parvovirus, les adénovirus, les polyomavirus, les herpèsvirus, les poxvirus, les papillomavirus humains, les paramyxovirus, les flavivirus, les alphavirus et les rhabdovirus.
(ZH)
双醋瑞因的一种制药用途,实验证明,双醋瑞因能够有效抑制嗜肝DNA病毒、逆转录病毒、肠道病毒、正黏病毒、纤丝病毒、呼肠孤病毒、沙粒病毒、戊型肝炎病毒、星状病毒、环状病毒、冠状病毒、细小病毒、腺病毒、多瘤病毒、疱疹病毒、痘病毒、人乳头瘤病毒、副黏病毒、黄病毒、甲病毒、弹状病毒。
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