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1. WO2020113529 - METHOD FOR CANCELLING INTERFERENCE OF THEOPHYLLINE IN IMMUNODETECTION AND IMMUNODETECTION KIT

Publication Number WO/2020/113529
Publication Date 11.06.2020
International Application No. PCT/CN2018/119617
International Filing Date 06.12.2018
IPC
G01N 33/53 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
CPC
G01N 33/53
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
Applicants
  • 深圳迈瑞生物医疗电子股份有限公司 SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD. [CN]/[CN]
Inventors
  • 李可 LI, Ke
  • 詹成雄 ZHAN, Chengxiong
  • 张裕平 ZHANG, Yuping
Agents
  • 北京派特恩知识产权代理有限公司 CHINA PAT INTELLECTUAL PROPERTY OFFICE
Priority Data
Publication Language Chinese (ZH)
Filing Language Chinese (ZH)
Designated States
Title
(EN) METHOD FOR CANCELLING INTERFERENCE OF THEOPHYLLINE IN IMMUNODETECTION AND IMMUNODETECTION KIT
(FR) PROCÉDÉ D'ANNULATION D'INTERFÉRENCE DE THÉOPHYLLINE EN IMMUNODÉTECTION ET KIT D'IMMUNODÉTECTION
(ZH) 免疫检测中消除茶碱干扰的方法及免疫检测试剂盒
Abstract
(EN)
A method for cancelling interference of theophylline in immunodetection and an immunodetection kit. The method for cancelling interference of theophylline in immunodetection comprises: carrying out an immunodetection reaction in the presence of a theophylline interference-resistant agent, the theophylline interference-resistant agent having a final concentration of 0.1 mg/mL-100 mg/mL, and being selected as at least one from a group consisting of free 6-mercaptopurine, 6-mercaptoguanine, 8-azguanine, hypoxanthine, adenine, purine, 2,6,8-trioxypurine, adenine nucleotide, and adenosine. The method and the kit can effectively reduce interference of theophylline on an immunodetection result.
(FR)
L'invention concerne un procédé d'annulation d'interférence de théophylline en immunodétection et un kit d'immunodétection. Le procédé d'annulation d'interférence de théophylline en immunodétection comprend : la réalisation d'une réaction d'immunodétection en présence d'un agent résistant aux interférences de théophylline, l'agent résistant aux interférences de théophylline ayant une concentration finale de 0,1 mg/mL à 100 mg/mL, et étant choisi dans le groupe constitué par la 6-mercaptopurine libre, la 6-mercaptoguanine, la 8-azguanine, l'hypoxanthine, l'adénine, la purine, la 2,6,8-trioxypurine, le nucléotide adénine et l'adénosine. Le procédé et le kit peuvent réduire efficacement le interférence de théophylline sur un résultat d'immunodétection.
(ZH)
免疫检测中消除茶碱干扰的方法及免疫检测试剂盒。免疫检测中消除茶碱干扰的方法包括:在抗茶碱干扰剂的存在下进行免疫检测反应,其中抗茶碱干扰剂的终浓度为0.1mg/mL~100mg/mL,且选自由6-巯基嘌呤、6-巯基鸟嘌呤、8-杂氮鸟、次黄嘌呤、腺嘌呤、嘌呤、2,6,8-三氧嘌呤、腺嘌呤核苷酸和腺苷所组成的组中的至少一种。该方法及试剂盒能有效降低茶碱对免疫检测结果的干扰。
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