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1. WO2020113527 - METHOD FOR DETECTING WHITE BLOOD CELLS, BLOOD CELL ANALYZER, AND STORAGE MEDIUM

Publication Number WO/2020/113527
Publication Date 11.06.2020
International Application No. PCT/CN2018/119614
International Filing Date 06.12.2018
IPC
C12M 1/36 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
36including condition or time responsive control, e.g. automatically controlled fermentors
G01N 15/14 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
15Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
10Investigating individual particles
14Electro-optical investigation
G01N 33/49 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
483Physical analysis of biological material
487of liquid biological material
49blood
CPC
C12M 1/36
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
1Apparatus for enzymology or microbiology
36including condition or time responsive control, e.g. automatically controlled fermentors
G01N 15/14
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
15Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
10Investigating individual particles
14Electro-optical investigation, e.g. flow cytometers
G01N 33/49
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
483Physical analysis of biological material
487of liquid biological material
49Blood
Applicants
  • 深圳迈瑞生物医疗电子股份有限公司 SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD. [CN]/[CN]
Inventors
  • 易秋实 YI, Qiushi
  • 代勇 DAI, Yong
  • 李进 LI, Jin
Agents
  • 北京派特恩知识产权代理有限公司 CHINA PAT INTELLECTUAL PROPERTY OFFICE
Priority Data
Publication Language Chinese (ZH)
Filing Language Chinese (ZH)
Designated States
Title
(EN) METHOD FOR DETECTING WHITE BLOOD CELLS, BLOOD CELL ANALYZER, AND STORAGE MEDIUM
(FR) PROCÉDÉ DE DÉTECTION DE GLOBULES BLANCS, ANALYSEUR DE GLOBULES BLANCS ET SUPPORT DE STOCKAGE
(ZH) 一种检测白细胞的方法、血液细胞分析仪及存储介质
Abstract
(EN)
Provided are a method for detecting white blood cells, a blood cell analyzer, and a storage medium. The method for detecting white blood cells is used for a blood cell analyzer, and comprises: obtaining first light signal information of particles of a first test sample, the first test sample being prepared by means of performing hemolysis and fluorescent staining on a blood sample (101); classifying and counting particles in the blood sample according to the first light signal information to obtain a first white blood cell particle group (102); according to the pulse width information of the first light signal information of the first white blood cell particle group, determining whether white blood cell aggregation is present in the first test sample (103); if it is determined that white blood cell aggregation is present in the first test sample, then rechecking the blood sample (104).
(FR)
Procédé de détection de globules blancs, analyseur de globules blancs e support de stockage. Le procédé de détection de globules blancs est utilisé pour un analyseur de cellules sanguines, et comprend les étapes consistant à : obtenir des premières informations de signal lumineux de particules d'un premier échantillon test, le premier échantillon test étant préparé au moyen d'une hémolyse et d'une coloration fluorescente sur un échantillon sanguin (101); à classer et à compter les particules dans l'échantillon de sang selon les premières informations de signal lumineux pour obtenir un premier groupe de particules de globules blancs (102); , à déterminer, en fonction des informations de largeur d'impulsion des premières informations de signal de lumière du premier groupe de particules de globules blancs, si une agrégation de globules blancs est présente dans le premier échantillon de test (103); à revérifier l'échantillon de sang (104), s'il est déterminé que l'agrégation de globules blancs est présente dans le premier échantillon d'essai.
(ZH)
一种检测白细胞的方法、血液细胞分析仪及存储介质。检测白细胞的方法用于血液细胞分析仪,包括:获取第一测试样本的粒子的第一光信号信息,其中第一测试样本通过对血液样本进行溶血处理和荧光染色处理而制备(101);根据第一光信号信息对血液样本中的粒子进行分类和计数以得到第一白细胞粒子群(102);根据第一白细胞粒子群的第一光信号信息的脉宽信息判断在第一测试样本中是否存在白细胞聚集(103);和当判定在第一测试样本中存在白细胞聚集时,对血液样本进行复检(104)。
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