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1. WO2020113263 - METHOD OF TREATMENT

Publication Number WO/2020/113263
Publication Date 11.06.2020
International Application No. PCT/AU2019/051317
International Filing Date 03.12.2019
IPC
A61K 39/395 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A61P 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
C07K 16/28 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
CPC
A61K 2039/505
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
505comprising antibodies
A61K 2039/804
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
80Vaccine for a specifically defined cancer
804Blood cells [leukemia, lymphoma]
A61K 2121/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
2121Preparations for use in therapy
A61P 35/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
02specific for leukemia
C07K 16/28
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
Applicants
  • HAEMALOGIX PTY LTD [AU]/[AU]
Inventors
  • DUNN, Rosanne
  • HERBERT, Ben R.
  • BREEN, Edmond J.
Agents
  • FB RICE PTY LTD
Priority Data
201890458103.12.2018AU
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHOD OF TREATMENT
(FR) PROCÉDÉ DE TRAITEMENT
Abstract
(EN)
The present disclosure relates to therapeutic combinations comprising an anti- KMA antibody and a proteasome inhibitor for the treatment of multiple myeloma. The present disclosure also relates to methods of treating multiple myeloma in subjects with high serum cytokine levels.
(FR)
La présente invention concerne des combinaisons thérapeutiques comprenant un anticorps anti-KMA et un inhibiteur de protéasome pour le traitement du myélome multiple. La présente invention concerne également des procédés de traitement du myélome multiple chez des sujets présentant des taux élevés de cytokine sérique.
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