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1. WO2020113233 - IRAK DEGRADERS AND USES THEREOF

Publication Number WO/2020/113233
Publication Date 04.06.2020
International Application No. PCT/US2019/064070
International Filing Date 02.12.2019
IPC
A61K 39/395 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A61K 47/64 2017.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
50the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
51the non-active ingredient being a modifying agent
62the modifying agent being a protein, peptide or polyamino acid
64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
A61K 47/68 2017.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
50the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
51the non-active ingredient being a modifying agent
68the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
CPC
A61K 39/395
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
395Antibodies
A61K 47/64
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
50the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
51the non-active ingredient being a modifying agent
62the modifying agent being a protein, peptide or polyamino acid
64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
A61K 47/68
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
50the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
51the non-active ingredient being a modifying agent
68the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
Applicants
  • KYMERA THERAPEUTICS, INC. [US]/[US]
Inventors
  • MAINOLFI, Nello
  • JI, Nan
  • KLUGE, Arthur F.
  • WEISS, Matthew M.
  • ZHANG, Yi
  • ZHENG, Xiaozhang
Agents
  • REID, Andrea L.C.
  • ARICO, Joseph W.
  • FLEMING, Paul R.
  • OH, Euk Charlie
  • PAGLIA, Danielle M.
  • WANG, Gang
  • PRAIRIE, Nicholas
  • DAVIS, Chad E.
  • STEVENSON, Christian
  • MACKLIN, Todd K.
  • DECHERT LLP
Priority Data
62/774,05130.11.2018US
62/788,46004.01.2019US
62/793,99218.01.2019US
62/826,74329.03.2019US
62/831,00708.04.2019US
62/851,42722.05.2019US
62/868,57428.06.2019US
62/875,34717.07.2019US
62/879,11726.07.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) IRAK DEGRADERS AND USES THEREOF
(FR) AGENTS DE DÉGRADATION DE KINASES DE TYPE IRAK ET LEURS UTILISATIONS
Abstract
(EN)
The present invention provides compounds, compositions thereof, and methods of using the same.
(FR)
La présente invention concerne des composés, des compositions de ceux-ci, et des procédés d'utilisation de ceux-ci.
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