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1. WO2020113224 - CHIMERIC ANTIGEN RECEPTOR FACTORIES AND METHODS OF USE THEREOF

Publication Number WO/2020/113224
Publication Date 04.06.2020
International Application No. PCT/US2019/064032
International Filing Date 02.12.2019
IPC
A61K 48/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
CPC
A61K 48/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Applicants
  • DANA-FARBER CANCER INSTITUTE, INC. [US]/[US]
Inventors
  • MARASCO, Wayne A.
  • ZHU, Quan Karen
  • WANG, Yufei
  • CHANG, Matthew
Agents
  • ESTRADA DE MARTIN, Paula
Priority Data
62/773,88530.11.2018US
62/826,46229.03.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) CHIMERIC ANTIGEN RECEPTOR FACTORIES AND METHODS OF USE THEREOF
(FR) RÉCEPTEUR D’ANTIGÈNE CHIMÈRE ET PROCÉDÉS D’UTILISATION DE CELUI-CI
Abstract
(EN)
This invention is directed to chimeric antigen receptors and cells comprising the same, wherein the cells further secrete monoclonal antibodies locally at a tumor site.
(FR)
La présente invention concerne des récepteurs antigéniques chimères et des cellules les comprenant, les cellules sécrétant en outre des anticorps monoclonaux localement au niveau d'un site tumoral.
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