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1. WO2020113213 - CYCLIC PANTETHEINE DERIVATIVES AND USES THEREOF

Publication Number WO/2020/113213
Publication Date 04.06.2020
International Application No. PCT/US2019/063986
International Filing Date 02.12.2019
IPC
C07F 9/6571 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
FACYCLIC, CARBOCYCLIC, OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
9Compounds containing elements of Groups 5 or 15 of the Periodic System
02Phosphorus compounds
547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
6564having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
6571having phosphorus and oxygen atoms as the only ring hetero atoms
C07F 9/6574 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
FACYCLIC, CARBOCYCLIC, OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
9Compounds containing elements of Groups 5 or 15 of the Periodic System
02Phosphorus compounds
547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
6564having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
6571having phosphorus and oxygen atoms as the only ring hetero atoms
6574Esters of oxyacids of phosphorus
A61K 31/665 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
66Phosphorus compounds
665having oxygen as a ring hetero atom, e.g. fosfomycin
CPC
A61K 31/665
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
66Phosphorus compounds
665having oxygen as a ring hetero atom, e.g. fosfomycin
A61K 45/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61P 25/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
A61P 29/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29Non-central analgesic, antipyretic or anti-inflammatory agents, e.g antirheumatic agents; Non-steroidal anti-inflammatory drugs (NSAIDs)
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
A61P 9/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9Drugs for disorders of the cardiovascular system
Applicants
  • COMET THERAPEUTICS, INC. [US]/[US]
Inventors
  • TAVERAS, Arthur George
  • KUSCER, Enej
  • SEKIRNIK, Angelina Roberta
  • SHAH, Dharini
  • VALLS SERÓN, Mercedes
Agents
  • ERLACHER, Heidi
  • ELRIFI, Ivor
  • SUN, Xixi
Priority Data
62/773,95230.11.2018US
62/774,75903.12.2018US
62/794,50318.01.2019US
62/795,49022.01.2019US
62/941,64327.11.2019US
62/941,64427.11.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) CYCLIC PANTETHEINE DERIVATIVES AND USES THEREOF
(FR) DÉRIVÉS DE PANTÉTHÉINE CYCLIQUE ET UTILISATIONS DE CEUX-CI
Abstract
(EN)
The present disclosure relates to compounds of Formula (I') or (II'-0): (Formulae (I'), (II'-0)), and pharmaceutically acceptable salts or solvates thereof. The present disclosure also relates to pharmaceutical compositions comprising the compounds and therapeutic and diagnostic uses of the compounds and pharmaceutical compositions.
(FR)
La présente invention concerne des composés de formule (I') ou (II'-0) : (Formulae (I'), (II'-0)), et des sels ou solvates pharmaceutiquement acceptables de ceux-ci. La présente invention concerne également des compositions pharmaceutiques contenant les composés, ainsi que des utilisations thérapeutiques et diagnostiques des composés et des compositions pharmaceutiques.
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