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1. WO2020113091 - OPHTHALMIC BRACHYTHERAPY SYSTEMS AND DEVICES FOR APPLICATION OF BETA RADIATION

Publication Number WO/2020/113091
Publication Date 04.06.2020
International Application No. PCT/US2019/063737
International Filing Date 27.11.2019
IPC
A61F 9/007 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
9Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
007Methods or devices for eye surgery
A61K 51/12 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
51Preparations containing radioactive substances for use in therapy or testing in vivo
12characterised by a special physical form, e.g. emulsion, microcapsules, liposomes
A61M 36/02 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
36Applying radioactive material to the body
02combined with other radiant- or wave-energy source, e.g. electromagnetic, thermal, microwave
A61M 36/04 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
36Applying radioactive material to the body
04Arrangements specially adapted for placing, e.g. inhaling or injecting, radioactive material within the body
A61M 36/12 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
36Applying radioactive material to the body
04Arrangements specially adapted for placing, e.g. inhaling or injecting, radioactive material within the body
12Injectors, holders for seeds or implants, e.g. capsules
A61N 5/10 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
5Radiation therapy
10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
CPC
A61N 2005/1089
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
5Radiation therapy
10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
1085characterised by the type of particles applied to the patient
1089Electrons
A61N 2005/1094
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
5Radiation therapy
10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
1092Details
1094Shielding, protecting against radiation
A61N 5/1017
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
5Radiation therapy
10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
1001using radiation sources introduced into or applied onto the body; brachytherapy
1014Intracavitary radiation therapy
1017Treatment of the eye, e.g. for "macular degeneration"
Applicants
  • MARSTELLER, Laurence, J. [US]/[US]
  • FAZIO, James, A. [US]/[US]
  • GEORGE, Harry, A. [US]/[US]
  • MURDOCH, Ian [US]/[US]
Inventors
  • MARSTELLER, Laurence, J.
  • FAZIO, James, A.
  • GEORGE, Harry, A.
  • MURDOCH, Ian
Agents
  • NGUYEN, Quan
Priority Data
62/772,74129.11.2018US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) OPHTHALMIC BRACHYTHERAPY SYSTEMS AND DEVICES FOR APPLICATION OF BETA RADIATION
(FR) SYSTÈMES ET DISPOSITIFS DE CURIETHÉRAPIE OPHTALMIQUE SERVANT À L'APPLICATION DE RAYONNEMENT BÊTA
Abstract
(EN)
Systems and devices for applying radiation to a target area, for example for maintaining functioning drainage blebs or functioning drainage holes in the eye, e.g., to reduce intraocular pressure (IOP) of an eye being treated for glaucoma. The systems and devices of the present invention provide for the application of beta radiation to the target area, wherein the beta radiation can function to inhibit or reduce the inflammation and/or fibrogenesis that may occur after insertion of an implant into the eye or introduction of a hole for the purpose of draining aqueous humor to maintain a healthy intraocular pressure. By reducing inflammation and/or fibrogenesis, the implant, the hole, the blebs, or other related structures or tissues can remain functioning appropriately.
(FR)
L'invention porte sur des systèmes et des dispositifs servant à l'application d'un rayonnement à une zone cible, par exemple pour maintenir le fonctionnement des bulles de drainage ou des trous de drainage de l’œil, par exemple, pour réduire la pression intraoculaire (PIO) d'un œil recevant un traitement contre le glaucome. Les systèmes et les dispositifs de la présente invention permettent l'application d'un rayonnement bêta à la zone cible, le rayonnement bêta pouvant fonctionner pour inhiber ou réduire l'inflammation et/ou la fibrogenèse qui peuvent se produire après l'insertion d'un implant dans l’œil ou l'introduction d'un trou dans le but de drainer l'humeur aqueuse afin de maintenir une pression intraoculaire saine. Par la réduction de l'inflammation et/ou la fibrogenèse, l'implant, le trou, les bulles ou d'autres structures ou tissus apparentés peuvent continuer de fonctionner de manière appropriée.
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