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1. WO2020113041 - METHODS FOR TREATING LIPID-RELATED DISEASES INCLUDING XANTHOMAS, CAROTID ARTERY STENOSES, AND CEREBRAL ATHEROSCLEROSIS

Publication Number WO/2020/113041
Publication Date 04.06.2020
International Application No. PCT/US2019/063659
International Filing Date 27.11.2019
IPC
A61K 35/16 2015.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
14Blood; Artificial blood
16Blood plasma; Blood serum
CPC
A61K 35/16
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
14Blood; Artificial blood
16Blood plasma; Blood serum
Applicants
  • HDL THERAPEUTICS, INC [US]/[US]
Inventors
  • BREWER, Hollis, Bryan, Jr.
  • MATIN, Michael, M.
Agents
  • DALAL, Sona
Priority Data
16/225,21019.12.2018US
16/409,54310.05.2019US
62/773,38830.11.2018US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHODS FOR TREATING LIPID-RELATED DISEASES INCLUDING XANTHOMAS, CAROTID ARTERY STENOSES, AND CEREBRAL ATHEROSCLEROSIS
(FR) MÉTHODES DE TRAITEMENT DE MALADIES LIÉES AUX LIPIDES, Y COMPRIS LES XANTHOMAS, LES STÉNOSES DES ARTÈRES CAROTIDES ET L'ATHÉROSCLÉROSE CÉRÉBRALE
Abstract
(EN)
Systems and methods for treating lipid-related diseases including xanthomas, carotid artery stenosis (CAS), and cerebral atherosclerosis (CA) and their complications use direct visualization or imaging techniques to assess the state of the anatomy at issue. A high density lipoprotein composition is made and administered to a patient in order to treat those lipid-related diseases. The administration is continued for a predetermined time or until certain anatomical changes are observed based on imaging, biomarker, or biopsy analysis.
(FR)
Des systèmes et des méthodes pour traiter des maladies liées aux lipides comprenant des xanthomas, une sténose des artères carotides (CAS) et une athérosclérose cérébrale (CA) et leurs complications utilisent des techniques de visualisation directe ou d'imagerie pour évaluer l'état de l'anatomie en question. Une composition de lipoprotéine haute densité est préparée et administrée à un patient afin de traiter ces maladies liées aux lipides. L'administration est poursuivie pendant un temps prédéterminé ou jusqu'à ce que certains changements anatomiques soient observés sur la base d'une imagerie, d'un biomarqueur ou d'une analyse de biopsie.
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