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1. WO2020112932 - USE OF DANTROLENE AND DANTROLENE PRODRUGS TO TREAT RADIATION EXPOSURE

Publication Number WO/2020/112932
Publication Date 04.06.2020
International Application No. PCT/US2019/063503
International Filing Date 27.11.2019
IPC
A61K 31/4166 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
41641,3-Diazoles
4166having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
A61P 39/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
39General protective or antinoxious agents
A61P 43/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43Drugs for specific purposes, not provided for in groups A61P1/-A61P41/108
CPC
A61K 31/4166
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
41641,3-Diazoles
4166having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
A61P 39/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
39General protective or antinoxious agents
A61P 43/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applicants
  • EAGLE PHARMACEUTICALS, INC. [US]/[US]
Inventors
  • HEPNER, Adrian
Agents
  • LODISE, Stephanie, A.
  • EDDE, Chantal, Francis
Priority Data
62/772,00127.11.2018US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) USE OF DANTROLENE AND DANTROLENE PRODRUGS TO TREAT RADIATION EXPOSURE
(FR) UTILISATION DE DANTROLÈNE ET DE PROMÉDICAMENTS DE DANTROLÈNE POUR TRAITER UNE EXPOSITION AU RAYONNEMENT
Abstract
(EN)
The disclosure is directed to methods of using dantrolene, dantrolene prodrugs, or pharmaceutically acceptable salts thereof, to treat radiation exposure.
(FR)
La divulgation concerne des méthodes d'utilisation de dantrolène, de promédicaments de dantrolène, ou de sels pharmaceutiquement acceptables de ceux-ci, pour traiter une exposition au rayonnement.
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