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1. WO2020112611 - CANCER DETECTION UTILIZING NORMAL TISSUE ADJACENT TO BREAST TUMORS WITH GENETIC ANCESTRY-MAPPING

Publication Number WO/2020/112611
Publication Date 04.06.2020
International Application No. PCT/US2019/062958
International Filing Date 25.11.2019
IPC
C12Q 1/68 2018.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
G01N 33/574 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
574for cancer
CPC
C12Q 1/68
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
68involving nucleic acids
G01N 33/574
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
574for cancer
Applicants
  • THE TRUSTEES OF INDIANA UNIVERSITY [US]/[US]
Inventors
  • NAKSHATRI, Harikrishna
Agents
  • ADDISON, Bradford G.
  • PILCHER, Jessamine G.
Priority Data
62/773,45730.11.2018US
62/795,21822.01.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) CANCER DETECTION UTILIZING NORMAL TISSUE ADJACENT TO BREAST TUMORS WITH GENETIC ANCESTRY-MAPPING
(FR) DÉTECTION DU CANCER À L'AIDE D'UN TISSU NORMAL ADJACENT À DES TUMEURS DU SEIN AVEC UN MAPPAGE D'ANCÊTRE GÉNÉTIQUE
Abstract
(EN)
Methods and compositions are provided for detecting and/or determining a patient's risk of cancer. The methods utilize categorizing the source of biopsy samples based on patient ancestry mapping in combination with cancer markers to identify patients at higher risk of cancer.
(FR)
L'invention concerne des procédés et des compositions pour détecter et/ou déterminer le risque de cancer d'un patient. Les procédés utilisent la catégorisation de la source d'échantillons de biopsie sur la base d'un mappage d'ancêtre de patient en combinaison avec des marqueurs de cancer pour identifier des patients présentant un risque élevé de cancer.
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