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1. WO2020112434 - COMPACT OPTICAL IMAGING SYSTEM FOR CELL CULTURE MONITORING

Publication Number WO/2020/112434
Publication Date 04.06.2020
International Application No. PCT/US2019/062137
International Filing Date 19.11.2019
IPC
C12M 1/12 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
12with sterilisation, filtration, or dialysis means
C12M 1/00 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
C12M 1/34 2006.01
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MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
34Measuring or testing with condition measuring or sensing means, e.g. colony counters
CPC
C12M 23/04
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
23Constructional details, e.g. recesses, hinges
02Form or structure of the vessel
04Flat or tray type, drawers
C12M 23/12
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MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
23Constructional details, e.g. recesses, hinges
02Form or structure of the vessel
12Well or multiwell plates
C12M 23/22
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12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
23Constructional details, e.g. recesses, hinges
22Transparent or translucent parts
C12M 31/08
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MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
31Means for providing, directing, scattering or concentrating light
08by conducting or reflecting elements located inside the reactor or in its structure
C12M 31/10
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
31Means for providing, directing, scattering or concentrating light
10by light emitting elements located inside the reactor, e.g. LED or OLED
C12M 41/46
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
41Means for regulation, monitoring, measurement or control, e.g. flow regulation
46of cellular or enzymatic activity or functionality, e.g. cell viability
Applicants
  • CORNING INCORPORATED [US]/[US]
Inventors
  • COBB, Joshua Monroe
  • SANSON, Mark Christian
Agents
  • RIGGS, F. Brock
Priority Data
62/773,89930.11.2018US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) COMPACT OPTICAL IMAGING SYSTEM FOR CELL CULTURE MONITORING
(FR) SYSTÈME D'IMAGERIE OPTIQUE COMPACT DE SURVEILLANCE DE CULTURE CELLULAIRE
Abstract
(EN)
An optical imaging system for cell culture monitoring is provided. The system includes an illumination segment having an illumination source and a collimating lens positioned between a first surface of a cell culture vessel and the illumination source. The illumination source and the collimating lens are arranged to transmit light through the first surface at an angle oblique to the first surface of the cell culture vessel. The system also includes a detection segment having a detector and a lens positioned between the first surface of the cell culture vessel and the detector. The lens focuses light to the detector through an aperture stop, and the detector receives light that exits the first surface of the cell culture vessel at an angle oblique to the first surface.
(FR)
L'invention concerne un système d'imagerie optique de surveillance de culture cellulaire. Le système comprend un segment d'éclairement comportant une source d'éclairement et une lentille de collimation positionnée entre une première surface d'un récipient de culture cellulaire et la source d'éclairement. La source d'éclairement et la lentille de collimation sont disposées de façon à transmettre la lumière à travers la première surface à un angle oblique par rapport à la première surface du récipient de culture cellulaire. Le système comprend également un segment de détection comportant un détecteur et une lentille positionnée entre la première surface du récipient de culture cellulaire et le détecteur. La lentille focalise la lumière vers le détecteur par l'intermédiaire d'un diaphragme, et le détecteur reçoit de la lumière qui sort de la première surface du récipient de culture cellulaire à un angle oblique par rapport à la première surface.
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