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1. WO2020112327 - FLOW CELL SYSTEMS AND METHODS RELATED TO SAME

Publication Number WO/2020/112327
Publication Date 04.06.2020
International Application No. PCT/US2019/060542
International Filing Date 08.11.2019
IPC
C12M 1/00 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
G01N 21/64 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
63optically excited
64Fluorescence; Phosphorescence
C12Q 1/00 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
CPC
B01L 2300/042
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2300Additional constructional details
04Closures and closing means
041Connecting closures to device or container
042Caps; Plugs
B01L 2300/0663
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2300Additional constructional details
06Auxiliary integrated devices, integrated components
0627Sensor or part of a sensor is integrated
0663Whole sensors
B01L 3/502
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3Containers or dishes for laboratory use, e.g. laboratory glassware
50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
502with fluid transport, e.g. in multi-compartment structures
G01N 2021/6439
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
63optically excited
64Fluorescence; Phosphorescence
6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
6439with indicators, stains, dyes, tags, labels, marks
G01N 2021/6482
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
63optically excited
64Fluorescence; Phosphorescence
645Specially adapted constructive features of fluorimeters
6482Sample cells, cuvettes
G01N 21/05
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
01Arrangements or apparatus for facilitating the optical investigation
03Cuvette constructions
05Flow-through cuvettes
Applicants
  • ILLUMINA, INC. [US]/[US]
Inventors
  • RIVAL, Arnaud
  • AGAH, Ali
  • DEHLINGER, Dietrich
  • FUNG, Tracy H.
  • CAI, Xiuyu
Agents
  • ZIEGLER, Kristian E.
Priority Data
62/771,19426.11.2018US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) FLOW CELL SYSTEMS AND METHODS RELATED TO SAME
(FR) SYSTÈMES DE CELLULES D’ÉCOULEMENT ET PROCÉDÉS ASSOCIÉS
Abstract
(EN)
Flow cells systems and corresponding methods are provided. The flow cells systems may include a socket comprising a base portion, a plurality of electrical contacts and a cover portion that includes a first port. The flow cells systems may also include a flow cell device secured within an enclosure of the socket. The flow cell device may comprise a frameless light detection device comprising a base wafer portion, a plurality of dielectric layers, a reaction structure, a plurality of light guides, a plurality of light sensors, and device circuitry electrically coupled to the light sensors. The flow cell device may also comprise a lid forming a flow channel over the reaction structure that includes a second port in communication with the flow channel and the first port of the socket. The device circuity of the light detection device may be electrically coupled to the electrical contacts of the socket.
(FR)
L'invention concerne des systèmes de cellules d'écoulement et des procédés correspondants. Les systèmes de cellules d'écoulement peuvent comprendre une prise comprenant une partie de base, une pluralité de contacts électriques et une partie de couvercle qui comprend un premier orifice. Les systèmes de cellules d'écoulement peuvent également comprendre un dispositif de cellule d'écoulement fixé à l'intérieur d'une enceinte de la prise. Le dispositif de cellule d'écoulement peut comprendre un dispositif de détection de lumière sans cadre comprenant une partie de tranche de base, une pluralité de couches diélectriques, une structure de réaction, une pluralité de guides de lumière, une pluralité de capteurs de lumière, et des circuits de dispositif couplés électriquement aux capteurs de lumière. Le dispositif de cellule d'écoulement peut également comprendre un couvercle formant un canal d'écoulement sur la structure de réaction qui comprend un second orifice en communication avec le canal d'écoulement et le premier orifice de la prise. Les circuits du dispositif de détection de lumière peuvent être couplés électriquement aux contacts électriques de la prise.
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