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1. WO2020112027 - METHOD OF DETECTING CANCER AND/OR TUBERCULOSIS

Publication Number WO/2020/112027
Publication Date 04.06.2020
International Application No. PCT/SG2019/050586
International Filing Date 28.11.2019
IPC
G01N 33/497 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
483Physical analysis of biological material
497of gaseous biological material, e.g. breath
CPC
A61B 5/082
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Detecting, measuring or recording for diagnostic purposes
08Detecting, measuring or recording devices for evaluating the respiratory organs
082Evaluation by breath analysis, e.g. determination of the chemical composition of exhaled breath
G01N 2033/4975
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
483Physical analysis of biological material
497of gaseous biological material, e.g. breath
4975other than oxygen, carbon dioxide or alcohol, e.g. organic vapours
G01N 33/57423
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
574for cancer
57407Specifically defined cancers
57423of lung
Applicants
  • NATIONAL UNIVERSITY OF SINGAPORE [SG]/[SG]
Inventors
  • JIA, Zhunan
  • VENKATESAN, Venky Thirumalai
  • LEE, Pyng
Agents
  • DAVIES COLLISON CAVE ASIA PTE. LTD.
Priority Data
10201810657R28.11.2018SG
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHOD OF DETECTING CANCER AND/OR TUBERCULOSIS
(FR) MÉTHODE DE DÉTECTION DE CANCER ET/OU DE TUBERCULOSE
Abstract
(EN)
The invention relates to a method of detecting the presence of cancer in a subject based on a panel of biomarkers comprising Hexanal, Heptanal, Octanal, Decanal, Benzaldehyde, Phenylacetaldehyde, Undecane and Benzoic acid in exhaled breath obtained from a subject. The disclosure also teaches a method of detecting tuberculosis and to distinguish the detection of tuberculosis from cancer or to distinguish the detection of cancer from tuberculosis.
(FR)
L'invention concerne une méthode de détection de la présence d'un cancer chez un sujet en fonction d'un panel de biomarqueurs comprenant l'hexanal, l'heptanal, l'octanal, le décanal, le benzaldéhyde, le phénylacétaldéhyde, le undécane et l'acide benzoïque dans l'air expiré obtenu auprès d'un sujet. L'invention concerne également une méthode de détection de la tuberculose, et permet de distinguer la détection de la tuberculose de celle du cancer ou de distinguer la détection du cancer de celle de la tuberculose.
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