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1. WO2020111895 - HYDROGEL PARTICLES FOR CHEMOEMBOLIZATION COMPRISING BIODEGRADABLE POLYMER

Publication Number WO/2020/111895
Publication Date 04.06.2020
International Application No. PCT/KR2019/016792
International Filing Date 29.11.2019
IPC
A61L 24/04 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
24Surgical adhesives or cements; Adhesives for colostomy devices
04containing macromolecular materials
A61L 24/10 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
24Surgical adhesives or cements; Adhesives for colostomy devices
04containing macromolecular materials
10Polypeptides; Proteins
A61L 24/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
24Surgical adhesives or cements; Adhesives for colostomy devices
A61B 17/12 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
17Surgical instruments, devices or methods, e.g. tourniquets
12for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A61K 31/4745 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
47Quinolines; Isoquinolines
4738ortho- or peri-condensed with heterocyclic ring systems
4745condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenanthrolines
A61P 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
CPC
A61B 17/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
17Surgical instruments, devices or methods, e.g. tourniquets
12for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
A61K 31/4745
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
47Quinolines; Isoquinolines
4738ortho- or peri-condensed with heterocyclic ring systems
4745condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
A61L 24/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
24Surgical adhesives or cements; Adhesives for colostomy devices
A61L 24/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
24Surgical adhesives or cements; Adhesives for colostomy devices
04containing macromolecular materials
A61L 24/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
24Surgical adhesives or cements; Adhesives for colostomy devices
04containing macromolecular materials
10Polypeptides; Proteins
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
Applicants
  • 주식회사 넥스트바이오메디컬 NEXTBIOMEDICAL CO., LTD. [KR]/[KR]
Inventors
  • 이일현 LI, Yi Xian
  • 최충렬 CHOI, Choong Ryeol
Agents
  • 윤대웅 YOON, Dae Woong
Priority Data
10-2018-015306430.11.2018KR
Publication Language Korean (KO)
Filing Language Korean (KO)
Designated States
Title
(EN) HYDROGEL PARTICLES FOR CHEMOEMBOLIZATION COMPRISING BIODEGRADABLE POLYMER
(FR) PARTICULES D'HYDROGEL POUR CHIMIOEMBOLISATION COMPRENANT UN POLYMÈRE BIODÉGRADABLE
(KO) 생분해성 고분자를 포함하는 화학색전용 수화겔 입자
Abstract
(EN)
The present invention relates to microparticles that can be used as drug-loaded hydrogel particles for embolization and a method for manufacturing same. The microparticles of the present invention have a very excellent anticancer agent adsorption ability, a short anticancer agent adsorption time, and a controllable decomposition time when administered in vivo. Therefore, when the microparticles of the present invention are used in chemoembolization, not only the anticancer effect is excellent, but also side effects can be minimized.
(FR)
La présente invention concerne des microparticules qui peuvent être utilisées en tant que particules d'hydrogel chargées de médicament en vue d'une embolisation et leur procédé de fabrication. Les microparticules de la présente invention ont une excellente capacité d'adsorption d'agent anticancéreux, un temps d'adsorption d'agent anticancéreux court, et un temps de décomposition contrôlable lorsqu'elles sont administrées in vivo. Par conséquent, lorsque les microparticules de la présente invention sont utilisées dans la chimioembolisation, non seulement l'effet anticancéreux est excellent, mais des effets secondaires peuvent également être minimisés.
(KO)
본 발명은 약물탑재형 색전용 수화겔 입자로 사용될 수 있는 마이크로 입자 및 이의 제조방법에 관한 것이다. 본 발명의 마이크로 입자는 항암제 흡착능력이 매우 우수하고, 항암제의 흡착시간이 짧을 뿐만 아니라 생체내 투여시 분해되는 시간을 조절할 수 있다. 따라서, 본 발명의 마이크로 입자를 화학색전에 이용하는 경우 항암 효과가 우수할 뿐만 아니라 부작용을 최소화할 수 있다.
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