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1. WO2020111809 - INFORMATION PROVIDING METHOD FOR PREDICTION OF BLOOD CANCER PROGNOSIS AFTER TRANSPLANTATION OF HEMATOPOIETIC STEM CELLS

Publication Number WO/2020/111809
Publication Date 04.06.2020
International Application No. PCT/KR2019/016556
International Filing Date 28.11.2019
IPC
C12Q 1/6886 2018.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
6883for diseases caused by alterations of genetic material
6886for cancer
CPC
C12Q 1/6886
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
68involving nucleic acids
6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
6883for diseases caused by alterations of genetic material
6886for cancer
Applicants
  • 가톨릭대학교 산학협력단 THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION [KR]/[KR]
Inventors
  • 김용구 KIM, Yong-Goo
  • 김명신 KIM, Myung-Shin
  • 이종미 LEE, Jong-Mi
  • 한은희 HAN, Eun-Hee
  • 박성수 PARK, Sung-Soo
Agents
  • 위병갑 WIE, Byoung-Gap
Priority Data
10-2018-015104129.11.2018KR
10-2019-011736924.09.2019KR
Publication Language Korean (KO)
Filing Language Korean (KO)
Designated States
Title
(EN) INFORMATION PROVIDING METHOD FOR PREDICTION OF BLOOD CANCER PROGNOSIS AFTER TRANSPLANTATION OF HEMATOPOIETIC STEM CELLS
(FR) PROCÉDÉ FOURNISSANT DES INFORMATIONS POUR LA PRÉDICTION DU PRONOSTIC DU CANCER DU SANG APRÈS LA TRANSPLANTATION DE CELLULES SOUCHES HÉMATOPOÏÉTIQUES
(KO) 조혈모세포 이식 후 혈액암 예후 예측을 위한 정보 제공 방법
Abstract
(EN)
The present invention relates to an information providing method for prediction of blood cancer prognosis after transplantation of hematopoietic stem cells. An NGS panel of the present invention can simultaneously analyse the minimal residual disease (MRD) of individuals transplanted with hematopoietic stem cells, and the chimerism of individuals transplanted with hematopoietic stem cells and donor individuals, and can accurately and rapidly predict the prognosis of blood cancers, including leukemia and lymphoma, and thus can be useful in related industries.
(FR)
Procédé fournissant des informations pour la prédiction du pronostic du cancer du sang après la transplantation de cellules souches hématopoïétiques. La présente invention fournit un panel NGS pouvant simultanément analyser la maladie résiduelle minimale (MRM) d'individus transplantés avec des cellules souches hématopoïétiques, et le chimérisme d'individus transplantés avec des cellules souches hématopoïétiques et des individus donneurs, et peut prédire avec précision et rapidement le pronostic de cancers du sang, y compris la leucémie et le lymphome, et peut donc être utile dans les industries connexes.
(KO)
본 발명은 조혈모세포 이식 후 혈액암 예후 예측을 위한 정보 제공 방법에 관한 것으로, 본 발명의 NGS 패널은 조혈모세포 이식된 개체의 미세잔존질환 (Minimal Residual Disease; MRD) 및 조혈모세포 이식된 개체와 공여 개체의 키메리즘을 동시에 분석 가능하므로, 정확하고 빠르게 백혈병 및 림프종 등을 포함하는 혈액암의 예후 예측할 수 있어, 관련 산업에 유용하게 이용할 수 있다.
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Latest bibliographic data on file with the International Bureau