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1. WO2020111265 - PIGMENTATION SKIN MODEL AND METHOD FOR PRODUCING SAME, AND METHOD FOR EVALUATING FACTOR FOR TREATING OR PREVENTING PIGMENTATION OF SKIN

Publication Number WO/2020/111265
Publication Date 04.06.2020
International Application No. PCT/JP2019/046886
International Filing Date 29.11.2019
IPC
C12M 1/00 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
C12M 1/34 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
34Measuring or testing with condition measuring or sensing means, e.g. colony counters
C12N 5/071 2010.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07Animal cells or tissues
071Vertebrate cells or tissues, e.g. human cells or tissues
C12Q 1/02 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
02involving viable microorganisms
CPC
C12M 1/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
1Apparatus for enzymology or microbiology
C12M 1/34
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
1Apparatus for enzymology or microbiology
34Measuring or testing with condition measuring or sensing means, e.g. colony counters
C12Q 1/02
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
02involving viable microorganisms
Applicants
  • 株式会社 資生堂 SHISEIDO COMPANY, LTD. [JP]/[JP]
Inventors
  • 山田 章子 YAMADA, Akiko
  • 小出 さやか KOIDE, Sayaka
  • ▲高▼木 雅哉 TAKAGI, Masaya
  • 相馬 勤 SOMA, Tsutomu
  • 福村 健太 FUKUMURA, Kenta
Agents
  • 青木 篤 AOKI, Atsushi
  • 三橋 真二 MITSUHASHI, Shinji
  • 渡辺 陽一 WATANABE, Yoichi
  • 中島 勝 NAKAJIMA, Masaru
  • 武居 良太郎 TAKEI, Ryotaro
  • 柴田 潤二 SHIBATA, Junji
Priority Data
2018-22602430.11.2018JP
Publication Language Japanese (JA)
Filing Language Japanese (JA)
Designated States
Title
(EN) PIGMENTATION SKIN MODEL AND METHOD FOR PRODUCING SAME, AND METHOD FOR EVALUATING FACTOR FOR TREATING OR PREVENTING PIGMENTATION OF SKIN
(FR) MODÈLE DE PIGMENTATION DE LA PEAU ET SON PROCÉDÉ DE PRODUCTION, ET PROCÉDÉ D'ÉVALUATION DU FACTEUR POUR LE TRAITEMENT OU LA PRÉVENTION DE LA PIGMENTATION DE LA PEAU
(JA) 色素沈着皮膚モデルおよびその製造方法、ならびに皮膚の色素沈着を治療または予防するための因子の評価方法
Abstract
(EN)
The present invention provides a pigmentation skin model that comprises: a first cell group containing fibroblasts damaged by light irradiation, said first cell group being seeded on a first cell culture substratum; and a second cell group containing melanocytes and keratinocytes, said second cell group being applied onto the first cell group. The present invention also provides a method for producing the pigmentation skin model, and a method for evaluating a factor for treating or preventing pigmentation of the skin, said method comprising using the pigmentation skin model.
(FR)
Modèle de pigmentation de la peau comprenant un premier groupe de cellules contenant des fibroblastes endommagés par une irradiation lumineuse, ledit premier groupe de cellules étant ensemencé sur un premier substrat de culture cellulaire; et un second groupe de cellules contenant des mélanocytes et des kératinocytes, ledit second groupe de cellules étant appliqué sur le premier groupe de cellules. La présente invention concerne en outre un procédé de production du modèle de pigmentation de la peau, et un procédé d'évaluation d'un facteur pour le traitement ou la prévention de la pigmentation de la peau, ledit procédé comprenant l'utilisation du modèle de pigmentation de la peau.
(JA)
本発明は、第1細胞培養基材の上に播種された、光照射により損傷が与えられた線維芽細胞を含む第1細胞群と;前記第1細胞群の上に適用された、メラノサイトとケラチノサイトとを含む第2細胞群と、を含む、色素沈着皮膚モデルを提供する。また、本発明は、色素沈着皮膚モデルを製造する方法、および、色素沈着皮膚モデルを用いた、皮膚の色素沈着を治療または予防するための因子の評価方法を提供する。
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