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1. WO2020111249 - THERAPEUTIC AGENT OF PERIPHERAL BLOOD FLOW DISORDER

Publication Number WO/2020/111249
Publication Date 04.06.2020
International Application No. PCT/JP2019/046847
International Filing Date 29.11.2019
IPC
A61P 9/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9Drugs for disorders of the cardiovascular system
A61P 9/08 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9Drugs for disorders of the cardiovascular system
08Vasodilators for multiple indications
A61P 9/10 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9Drugs for disorders of the cardiovascular system
10for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
A61K 35/545 2015.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
48Reproductive organs
54Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
545Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
CPC
A61K 35/545
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
48Reproductive organs
54Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
545Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
A61P 9/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9Drugs for disorders of the cardiovascular system
A61P 9/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9Drugs for disorders of the cardiovascular system
08Vasodilators for multiple indications
A61P 9/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9Drugs for disorders of the cardiovascular system
10for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applicants
  • 京都府公立大学法人 KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION [JP]/[JP]
  • 株式会社生命科学インスティテュート LIFE SCIENCE INSTITUTE, INC. [JP]/[JP]
Inventors
  • 的場 聖明 MATOBA, Satoaki
  • 出澤 真理 DEZAWA, Mari
Agents
  • 特許業務法人秀和特許事務所 IP FIRM SHUWA
Priority Data
2018-22529530.11.2018JP
Publication Language Japanese (JA)
Filing Language Japanese (JA)
Designated States
Title
(EN) THERAPEUTIC AGENT OF PERIPHERAL BLOOD FLOW DISORDER
(FR) AGENT THÉRAPEUTIQUE CONTRE UN TROUBLE DU FLUX SANGUIN PÉRIPHÉRIQUE
(JA) 末梢血流障害の治療剤
Abstract
(EN)
Provided is a cell preparation for treating a peripheral blood flow disorder, the cell preparation including pluripotent stem cells (Muse cells) which are SSEA-3 positive and derived from mesenchymal tissues of a living body or cultured mesenchymal cells. The peripheral blood flow disorder is preferably a peripheral arterial disease, and more preferably, chronic arterial obstruction of the limbs.
(FR)
L'invention concerne une préparation cellulaire pour traiter un trouble du flux sanguin périphérique, la préparation cellulaire comprenant des cellules souches pluripotentes (cellules Muse) qui sont SSEA-3 positives et dérivées de tissus mésenchymateux d'un corps vivant ou de cellules mésenchymateuses cultivées. Le trouble du flux sanguin périphérique est de préférence une maladie artérielle périphérique, et de préférence, une obstruction artérielle chronique des membres.
(JA)
生体の間葉系組織又は培養間葉系細胞に由来するSSEA-3陽性の多能性幹細胞(Muse細胞)を含む、末梢血流障害を治療するための細胞製剤。末梢血流障害は好ましくは末梢動脈疾患であり、より好ましくは四肢の慢性動脈閉塞症である。
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