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1. WO2020110137 - FOLLICULAR FLUID ASPIRATION

Note: Text based on automatic Optical Character Recognition processes. Please use the PDF version for legal matters

[ EN ]

AMENDED CLAIMS

received by the International Bureau on 13 January 2020 (13.01.2020)

I/ We claim:

1. An ovum pick up (OPU) device (200) for aspirating follicular fluid from ovarian follicles, the OPU device (200) comprising:

a needle (202) having a first end (202-1 ) and a second end (202-2), opposite to the first end (202-1 ), wherein the first end (202-1 ) of the needle (202) is to pierce through an ovarian follicle to aspirate the follicular fluid from the ovarian follicle by a suction force;

a connector (204) having a channel (206) to receive the second end (202-2) of the needle (202); and

an elastic tube (210) connected to the connector (204), wherein the second end (202-2) of the needle (202) passes through the channel (206) and inside the elastic tube (210), wherein the elastic tube (210) is compressible, while locating the ovarian follicle and piercing the needle (202) through the ovarian follicle, to regulate the suction force during aspiration of the follicular fluid,

wherein the connector (204) comprises:

a main body (205), wherein the channel (206) is a through hole formed in the main body (205); and

a handle protruding out from the main body (205), wherein the handle extends parallel to the elastic tube (210) and along a length of the elastic tube (210).

2. The OPU device (200) as claimed in claim 1 , wherein the elastic tube (210) is compressible to reduce the suction force and decompressible to increase the suction force.

3. The OPU device (200) as claimed in claim 1 , wherein the handle is parallel to a horizontal plane passing through the elastic tube (210).

4. The OPU device (200) as claimed in claim 1 , wherein the handle (208) has a cylindrical shape and a pinch profile in a portion thereof, wherein the pinch profile (500) has a cross-sectional shape with:

a first edge proximal to the elastic tube (210); and

a second edge opposite to the first edge and distal to the elastic tube (210), the first edge being of a smaller length than a length of the second edge and a cross-sectional diameter of the elastic tube (210).

5. The OPU device (200) as claimed in claim 4, wherein the cross-sectional shape is further with:

a third edge connecting a first endpoint of the first edge to a first endpoint of the second edge, the first endpoint of the first edge and the first end point of the second edge being positioned on a first side of a vertical plane passing through a longitudinal axis of the handle (208); and

a fourth edge, opposite to the third edge, connecting a second endpoint of the first edge to a second endpoint of the second edge, the second endpoint of the first edge and the second end point of the second edge being positioned on a second side, opposite to the first side, of the vertical plane.

6. The OPU device (200) as claimed in claim 5, wherein each of the third edge and the fourth edge has a straight-line profile.

7. The OPU device (200) as claimed in claim 5, wherein each of third edge and the fourth edge has a curved profile.

8. The OPU device (200) as claimed in claim 7, wherein the curved profile has one crest and one trough.

9. The OPU device (200) as claimed in claim 1 , wherein the handle (208) is separated from the elastic tube by a distance ranging from about 0.5 mm to about 10 mm.

10. The OPU device (200) as claimed in claim 1 , wherein the handle (208) has a width ranging from about 0.5 cm to about 2 cm.

1 1. The OPU device (200) as claimed in claim 1 , wherein the handle (208) has a height ranging from about 0.5 cm to about 3 cm.

12. The OPU device (200) as claimed in claim 1 , wherein the handle (208) is positioned with respect to the elastic tube (210), such that the elastic tube (210) is pinchable by movement of an index finger and a thumb towards each other, while the handle (208) is gripped between the index finger and the thumb.

13. The OPU device (200) as claimed in claim 12, wherein the elastic tube (210) is compressible when pinched between the index finger and the thumb.

14. The OPU device (200) as claimed in claim 1 , wherein the handle (602) is perpendicular to the horizontal plane passing through the elastic tube (210), and wherein the handle (602) has a first end (604) proximal to the needle (202), the first end (604) being coupled to the connector (204), and a second end (606) opposite to the first end (604), the second end (606) being coupled to a connecting tube (108) that is to carry the follicular fluid from the elastic tube (210) to a collection chamber (102).

15. The OPU device (200) as claimed in claim 13, wherein the handle (602) has a first pair of projections (608) at the first end (604), such that a portion of the connector (204) is held between the first pair of projections (608).

16. The OPU device (200) as claimed in claim 13, wherein the handle (602) has a second pair of projections (610) at the second end (606), such that a portion of the connecting tube (108) is held between the second pair of projections (610).

17. The OPU device (200) as claimed in claim 13, wherein the handle (602) has a width greater than a cross-sectional diameter of the elastic tube (210).

18. The OPU device (200) as claimed in claim 1 , wherein the elastic tube (210) has a length ranging from about 1 cm to about 10 cm.

19. The OPU device (200) as claimed in claim 1 , wherein the elastic tube (210) has an inner diameter one of equal to and greater than an outer diameter of the needle.

20. The OPU device (200) as claimed in claim 1 , wherein the elastic tube (210) is made of one of rubber or silicon.

21 . A system (100) for aspirating a follicular fluid from ovarian follicles, the system (100) comprising:

a collection chamber (102) for accumulation of the follicular fluid;

a suction pump (104) coupled to the collection chamber (102), wherein the suction pump (104) is to generate a suction force to aspirate the follicular fluid from an ovarian follicle;

a needle (202) having a first end and a second end, opposite to the first end, wherein the first end of the needle (202) is to pierce through the ovarian follicle to draw the follicular fluid from the ovarian follicle by the suction force;

a connector (204) having a channel (206) to receive the second end of the needle (202); and

a first elastic tube (210) connected to the connector (204), wherein the second end of the needle (202) passes through the channel (206) and inside the first

elastic tube (210), wherein the first elastic tube (210) is compressible, while locating the ovarian follicle and piercing the needle (202) through the ovarian follicle simultaneously, to regulate the suction force during aspiration of the follicular fluid,

wherein the connector (204) comprises:

a main body (205), wherein the channel (205) is a through hole formed in the main body (205); and

a handle integral to the main body (205), wherein the handle is parallel to the first elastic tube (210) and extends along a length of the first elastic tube (210).

22. The system (100) as claimed in claim 21 , further comprising:

a set of collection chambers connected between the suction pump (104) and the collection chamber (102), wherein collection chambers in the set are connected through a cascade connection of connector pipes.

23. The system (100) as claimed in claim 21 , wherein the first elastic tube (210) is compressible to reduce the suction force and decompressible to increase the suction force.

24. The system (100) as claimed in claim 21 , wherein the handle is parallel to a horizontal plane passing through the elastic tube (210).

25. The system (100) as claimed in claim 21 , wherein the handle (208) is separated from the first elastic tube (210) by a distance ranging from about 0.5 mm to about 10 mm.

26. The system (100) as claimed in claim 21 , wherein the handle (208) has a width ranging from about 0.5 cm to about 2 cm.

27. The system (100) as claimed in claim 21 , wherein the handle (208) has a height ranging from about 0.5 cm to about 3 cm.

28. The system (100) as claimed in claim 21 , wherein the handle (208) is positioned parallel to the first elastic tube (210), such that the first elastic tube (210) is pinchable by movement of an index finger and a thumb towards each other, while the handle is gripped between the index finger and the thumb.

29. The system (100) as claimed in claim 21 , wherein the handle (208) has a cylindrical shape and a pinch profile in a portion thereof, wherein the pinch profile (500) has a cross-sectional shape with:

a first edge proximal to the elastic tube (210); and

a second edge opposite to the first edge and distal to the elastic tube (210), the first edge being of a smaller length than a length of the second edge and a cross-sectional diameter of the elastic tube (210).

30. The system (100) as claimed in claim 21 , wherein the cross-sectional shape is further with:

a third edge connecting a first endpoint of the first edge to a first endpoint of the second edge, the first endpoint of the first edge and the first end point of the second edge being positioned on a first side of a vertical plane passing through a longitudinal axis of the handle (208); and

a fourth edge, opposite to the third edge, connecting a second endpoint of the first edge to a second endpoint of the second edge, the second endpoint of the first edge and the second end point of the second edge being positioned on a second side, opposite to the first side, of the vertical plane.

31 . The system (100) as claimed in claim 21 , wherein the handle (602) is perpendicular to the horizontal plane passing through the elastic tube (210), and wherein the handle (602) has a first end (604) proximal to the needle (202), the first end (604) being coupled to the connector (204), and a second end (606) opposite to the first end (604), the second end (606) being coupled to a connecting tube (108) that is to carry the follicular fluid from the elastic tube (210) to a collection chamber (102).

32. The system (100) as claimed in claim 31 , wherein the handle (602) has a first pair of projections (608) at the first end (604), such that a portion of the connector (204) is held between the first pair of projections (608).

33. The system (100) as claimed in claim 28, wherein the handle (602) has a second pair of projections (610) at the second end (606), such that a portion of the connecting tube (108) is held between the second pair of projections (610).

34. The system (100) as claimed in claim 31 , wherein the handle (602) has a width greater than a cross-sectional diameter of the elastic tube (210).

35. The system (100) as claimed in claim 21 , further comprising:

a connecting tube (108) having a first end (108-1 ) coupled to an end of the first elastic tube (210) and a second end (108-2) facing towards the collection chamber (102), wherein the connecting tube (108) is to carry the follicular fluid from the first elastic tube (210) to the collection chamber (102).

36. The system (100) as claimed in claim 21 , further comprising:

an ultrasound probe on which a needle guide (306) is mounted through which the needle (202) is passed, wherein the ultrasound probe is to guide the first end of the needle (202-1 ) towards the ovarian follicle.

37. The system (100) as claimed in claim 35, further comprising:

a second elastic tube (1 10) connected between the connecting tube (108) and the collection chamber (1 02), wherein an end of the second elastic tube (1 1 0) is proximal to the collection chamber (102) and the second elastic tube (1 1 0) is compressible to control backflow of follicular fluid into the ovary while the collection chamber is replaced.

38. The system (100) as claimed in claim 37, wherein the length of the second elastic tube (1 10) ranges between about 1 cm to about 2 cm.