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1. WO2020110114 - A PEPTIDE, A COMPLEX AND A METHOD FOR TREATING CANCER

Publication Number WO/2020/110114
Publication Date 04.06.2020
International Application No. PCT/IL2019/051294
International Filing Date 27.11.2019
IPC
A61K 38/03 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
03Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof
A61K 38/10 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
10Peptides having 12 to 20 amino acids
A61P 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
CPC
A61K 38/03
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
03Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof
A61K 38/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
10Peptides having 12 to 20 amino acids
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
Applicants
  • TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED [IL]/[IL]
Inventors
  • CIECHANOVER, Aaron
  • KRAVTSOVA, Yelena
  • GOLDHIRSH, Gilad
Agents
  • GORDON, Irit
  • FRIEDMAN, Nathalie
  • FISHER, Michal
  • GORDON, Irit
  • SILVERMAN, Eran
  • SILMAN, Jonathan
Priority Data
62/772,89229.11.2018US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) A PEPTIDE, A COMPLEX AND A METHOD FOR TREATING CANCER
(FR) PEPTIDE, COMPLEXE ET PROCÉDÉ DE TRAITEMENT DU CANCER
Abstract
(EN)
A peptide comprising the amino acid sequence set forth in WILVRLW (SEQ ID NO: 1), or any functionally related variant thereof, a complex, conjugate or chimera comprising the same, wherein the peptide is linked with or without a linker to RING or to a molecule or peptide that recruits E3 ligase and method for treating cancer by administering the same.
(FR)
La présente invention concerne un peptide comprenant la séquence d’acides aminés exposée dans WILVRLW (SEQ ID no : 1), ou un quelconque variant fonctionnellement apparenté de ce dernier, un complexe, un conjugué ou une chimère le comprenant, le peptide étant lié avec, ou sans, lieur à RING ou à une molécule ou un peptide qui recrute la E3 ligase et un procédé de traitement du cancer par son administration.
Latest bibliographic data on file with the International Bureau