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1. WO2020109801 - IMPROVED MICROFLUIDIC DEVICES, SYSTEMS AND METHODS

Publication Number WO/2020/109801
Publication Date 04.06.2020
International Application No. PCT/GB2019/053367
International Filing Date 28.11.2019
IPC
B01L 3/00 2006.01
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
B01L 7/00 2006.01
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
7Heating or cooling apparatus; Heat insulating devices
CPC
B01L 2300/0816
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2300Additional constructional details
08Geometry, shape and general structure
0809rectangular shaped
0816Cards, e.g. flat sample carriers usually with flow in two horizontal directions
B01L 2300/0883
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2300Additional constructional details
08Geometry, shape and general structure
0861Configuration of multiple channels and/or chambers in a single devices
0883Serpentine channels
B01L 2400/0481
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2400Moving or stopping fluids
04Moving fluids with specific forces or mechanical means
0475specific mechanical means and fluid pressure
0481squeezing of channels or chambers
B01L 3/50273
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3Containers or dishes for laboratory use, e.g. laboratory glassware
50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
502with fluid transport, e.g. in multi-compartment structures
5027by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
50273characterised by the means or forces applied to move the fluids
B01L 7/525
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
7Heating or cooling apparatus
52with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
525with physical movement of samples between temperature zones
Applicants
  • QUANTUMDX GROUP LIMITED [GB]/[GB]
Inventors
  • MADADI, Hojjat
  • WILLSHARE, Thomas Michael
  • PAGE, Robin
Agents
  • DEFINITION IP LIMITED
Priority Data
1819419.129.11.2018GB
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) IMPROVED MICROFLUIDIC DEVICES, SYSTEMS AND METHODS
(FR) DISPOSITIFS, SYSTÈMES ET PROCÉDÉS MICROFLUIDIQUES AMÉLIORÉS
Abstract
(EN)
The present invention relates to microfluidic devices, such as cassettes for diagnostics, which allow for on-cassette processing including amplification by polymerase chain reaction (PCR), and systems and methods of using the same, wherein microfluidic cassette is pressurised prior to amplification of nucleic acid in said sample in an amplification/PCR section of the device.
(FR)
La présente invention concerne des dispositifs microfluidiques, tels que des cassettes pour le diagnostic, qui permettent un traitement sur cassette comprenant l'amplification par réaction en chaîne de la polymérase (PCR), et des systèmes et des procédés d'utilisation de ceux-ci, la cassette microfluidique étant mise sous pression avant l'amplification de l'acide nucléique dans ledit échantillon dans une section d'amplification/PCR du dispositif.
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