Processing

Please wait...

Settings

Settings

Goto Application

1. WO2020109792 - ANTIBACTERIAL ANTISENSE AGENTS


Disclaimer The image version (PDF) available on PATENTSCOPE is the official version. This online html version is provided to assist users. Despite the great care taken in its compilation to ensure a precise and accurate representation of the data appearing on the printed document/images, errors and/or omissions cannot be excluded due to the data transmittal, conversion and inherent limitations of the (optional) machine translation processes used. Hyperlinks followed by this symbol , are to external resources that are not controlled by WIPO. WIPO disclaims all liability regarding the above points.

INTERNATIONAL SEARCH REPORT (ISR)
Part 1:  1  2  3  4  5  6          Part 2:  A  B  C  D  E 
International application No. Applicant's or agent's file reference
PCT/GB2019/053354 P262295WO/AC
International filing date (day/month/year) (Earliest) Priority Date (day/month/year)
27 November 2019 28 November 2018
Applicant
PEDANIUS THERAPEUTICS LIMITED
FOR FURTHER ACTION: See Form PCT/ISA/220 as well as, where applicable, item 5 below.
This international search report has been prepared by this International Searching Authority and is transmitted to the applicant according to Article 18. A copy is being transmitted to the International Bureau.
It is also accompanied by a copy of each prior art document cited in this report.
1. Basis of the report
a. With regard to the language, the international search was carried out on the basis of:
the international application in the language in which it was filed.
a translation of the international application into                                          which is the language of a translation furnished for the purposes of international search (Rules 12.3(a) and 23.1(b)).
b.
This international search report has been established taking into account the rectification of an obvious mistake authorized by or notified to this Authority under Rule 91 (Rule 43.6bis(a)).
c.
1. With regard to any nucleotide and/or amino acid sequence disclosed in the international application, the international search was carried out on the basis of a sequence listing:
a. forming part of the international application as filed:
in the form of an Annex C/ST.25 text file.
on paper or in the form of an image file.
b. furnished together with the international application under PCT Rule 13ter.1(a) for the purposes of international search only in the form of an Annex C/ST.25 text file.
c. furnished subsequent to the international filing date for the purposes of international search only:
in the form of an Annex C/ST.25 text file (Rule 13ter.1(a)).
on paper or in the form of an image file (Rule 13ter.1(b) and Administrative Instructions, Section 713).
2.
In addition, in the case that more than one version or copy of a sequence listing has been filed or furnished, the required statements that the information in the subsequent or additional copies is identical to that forming part of the application as filed or does not go beyond the application as filed, as appropriate, were furnished.
3.
Additional comments:
2. Certain claims were found unsearchable
3. Unity of invention is lacking
4. Title of the invention
The text is approved as submitted by the applicant.
The text has been established by this Authority to read as follows:
5. Abstract
The text is approved as submitted by the applicant.
The text has been established, according to Rule 38.2, by this Authority as it appears in Box No. IV. The applicant may, within one month from the date of mailing of this international search report, submit comments to this Authority.
6. Drawings
a.
The figure of the drawings to be published with the abstract is Figure No. ____________
as suggested by the applicant.
as selected by this Authority, because the applicant failed to suggest a figure.
as selected by this Authority, because this figure better characterizes the invention.
b.
none of the figures is to be published with the abstract.

A. CLASSIFICATION OF SUBJECT MATTER

     C12N 15/113 (2010.01)i; A61K 31/7088 (2006.01)i; A61K 47/54 (2017.01)i; A61P 31/04 (2006.01)i
According to International Patent Classification (IPC) or to both national classification and IPC

B. FIELDS SEARCHED

Minimum documentation searched (classification system followed by classification symbols):
     C12N; A61K; A61P
Documentation searched other than minimum documentation to the extent that such documents are included in the fields searched:
Electronic data base consulted during the international search (name of data base and, where practicable, search terms used):
EPO-Internal, WPI Data, CHEM ABS Data, BIOSIS, Sequence Search, EMBASE, EMBL

C. DOCUMENTS CONSIDERED TO BE RELEVANT

Category* Citation of document, with indication, where appropriate, of the relevant passages Relevant to claim No.
(1)
Y
WO 2006104530 A1 (CELL WORKS THERAPEUTICS INC [US]; DUFF ROBERT [US]) 05 October 2006 (2006-10-05)
1-34
claims 1,3,6,11
(2)
Y
WO 2014002039 A1 (SHIRE AG [CH]) 03 January 2014 (2014-01-03)
1-34
claims 1,4,7,8,37
(3)
A
WO 2015006740 A2 (ALNYLAM PHARMACEUTICALS INC [US]) 15 January 2015 (2015-01-15)
1-34
page 45 - page 46; claims 1-4
(4)
A
HEGARTY JOHN P ET AL, "Advances in therapeutic bacterial antisense biotechnology", 05 December 2017 (2017-12-05), Vol. 102, No. 3, page 1055-1065,
XP036390096
[retrieved on  2017-12-05]
1-34
figures 1,2; tables 1,3
(5)
A
MATTHIEU FONVIELLE ET AL, "Electrophilic RNA for Peptidyl-RNA Synthesis and Site-Specific Cross-Linking with tRNA-Binding Enzymes", ANGEWANDTE CHEMIE, INTERNATIONAL EDITION,Vol. 55, No. 43, 26 September 2016 (2016-09-26), page 13553-13557,
XP055675927
1-34
scheme 2;figure 1
(6)
A
EP 3323893 A1 (KYOWA HAKKO KIRIN CO LTD [JP]) 23 May 2018 (2018-05-23)
1-34
paragraphs [0040], [0043]; claims 1-6
(7)
A
GB 2020665 A (HIRAI Y; YAMAMURA Y; KISHIMOTO T; AZUMA I) 21 November 1979 (1979-11-21)
1-34
claims 1-8
(8)
A
XIAO-YAN XUE ET AL, "Advances in the delivery of antisense oligonucleotides for combating bacterial infectious diseases", NANOMEDICINE: NANOTECHNOLOGY, BIOLOGY AND MEDICINE,Vol. 14, No. 3, 16 January 2018 (2018-01-16), page 745-758,
XP055676062
1-34
table 1
(9)
A
BRUCE L GELLER ET AL, "Morpholino oligomers tested in vitro, in biofilm and in vivo against multidrug-resistant Klebsiella pneumoniae", JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY.,Vol. 73, No. 6, 01 March 2018 (2018-03-01), page 1611-1619,
XP055602138
1-34
figure 1; table 1
(10)
A
T. P. PRAKASH ET AL, "Targeted delivery of antisense oligonucleotides to hepatocytes using triantennary N-acetyl galactosamine improves potency 10-fold in mice", NUCLEIC ACIDS RESEARCH,Vol. 42, No. 13, 03 July 2014 (2014-07-03), page 8796-8807,
XP055148318
1-34
figures 1-3
(11)
A
WO 2016172615 A1 (UNIV DELAWARE [US]; GRIMES CATHERINE LEIMKUHLER [US] ET AL.) 27 October 2016 (2016-10-27)
1-34
the whole document
*
Special categories of cited documents:
"A"
document defining the general state of the art which is not considered to be of particular relevance
"D"
document cited by the applicant in the international application
"E"
earlier application or patent but published on or after the international filing date
"L"
document which may throw doubts on priority claim(s) or which is cited to establish the publication date of another citation or other special reason (as specified)
"O"
document referring to an oral disclosure, use, exhibition or other means
"P"
document published prior to the international filing date but later than the priority date claimed
"T"
later document published after the international filing date or priority date and not in conflict with the application but cited to understand the principle or theory underlying the invention
"X"
document of particular relevance; the claimed invention cannot be considered novel or cannot be considered to involve an inventive step when the document is taken alone
"Y"
document of particular relevance; the claimed invention cannot be considered to involve an inventive step when the document is combined with one or more other such documents, such combination being obvious to a person skilled in the art
"&"
document member of the same patent family

D. INFORMATION ON PATENT FAMILY MEMBERS

Patent document cited in search report Publication date
(day/month/year)
Patent family member(s) Publication date
(day/month/year)
WO 2006104530 A1
05 October 2006
NONE
WO 2014002039 A1
03 January 2014
US 2014073589 A1
WO 2014002039 A1
13 March 2014
03 January 2014
WO 2015006740 A2
15 January 2015
AU 2014287002 A1
CA 2917161 A1
EP 3019200 A2
JP 2016529230 A
US 2016376585 A1
WO 2015006740 A2
11 February 2016
15 January 2015
18 May 2016
23 September 2016
29 December 2016
15 January 2015
EP 3323893 A1
23 May 2018
EP 3323893 A1
JP WO2017010575 A1
TW 201718030 A
US 2018193471 A1
WO 2017010575 A1
23 May 2018
26 April 2018
01 June 2017
12 July 2018
19 January 2017
GB 2020665 A
21 November 1979
DE 2912865 A1
FR 2421178 A1
GB 2020665 A
JP S54130516 A
18 October 1979
26 October 1979
21 November 1979
09 October 1979
WO 2016172615 A1
27 October 2016
US 2018298061 A1
WO 2016172615 A1
18 October 2018
27 October 2016
Name and mailing address of the ISA/:
European Patent Office
P.B. 5818, Patentlaan 2, 2280 HV Rijswijk,
Netherlands
Telephone No. (+31-70)340-2040
Facsimile No. (+31-70)340-3016
Date of the actual completion of the international search:
12 March 2020
Date of mailing of the international search report:
20 March 2020
Authorized officer:
Bucka, Alexander
Top    Part 1: 1 2 3 4 5 6         Part 2: A B C D E