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1. WO2020109542 - TREATMENT OF ACUTE GVHD USING DONOR-SPECIFIC ANTI-HLA ANTIBODIES

Publication Number WO/2020/109542
Publication Date 04.06.2020
International Application No. PCT/EP2019/083070
International Filing Date 29.11.2019
IPC
C07K 16/28 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
A61P 37/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37Drugs for immunological or allergic disorders
CPC
A61K 2039/505
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
505comprising antibodies
A61P 37/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37Drugs for immunological or allergic disorders
C07K 16/2833
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
2803against the immunoglobulin superfamily
2833against MHC-molecules, e.g. HLA-molecules
C07K 2317/10
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2317Immunoglobulins specific features
10characterized by their source of isolation or production
Applicants
  • ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS [FR]/[FR]
  • ETABLISSEMENT FRANCAIS DU SANG [FR]/[FR]
Inventors
  • ZUBER, Julien
  • JOLLET, Isabelle
  • TAUPIN, Jean-Luc
Agents
  • REGIMBEAU
Priority Data
18306583.829.11.2018EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) TREATMENT OF ACUTE GVHD USING DONOR-SPECIFIC ANTI-HLA ANTIBODIES
(FR) TRAITEMENT D'UNE GVH AIGUË À L'AIDE D'ANTICORPS ANTI-HLA SPÉCIFIQUES À UN DONNEUR
Abstract
(EN)
The present invention is in the field of graft versus host disease treatment and relates to a composition for use in the treatment of acute Graft-versus-Host Disease (GVHD) in a transplantation recipient after allogenic transplantation with at least one solid organ and/or hematopoietic cells (HC) from a human leucocyte antigen (HLA)-mismatched transplantation donor.
(FR)
La présente invention se rapporte au domaine du traitement de la maladie du greffon contre l'hôte et concerne une composition destinée à être utilisée dans le traitement d'une maladie aiguë du greffon contre l'hôte (GVH) chez un receveur d’une greffe après transplantation allogénique avec au moins un organe solide et/ou des cellules hématopoïétiques (HC) à partir d'un donneur de transplantation non apparié à l'antigène leucocytaire humain (HLA).
Also published as
Latest bibliographic data on file with the International Bureau