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1. WO2020109523 - NOVEL TUMOR ANTIGEN BINDING AGENTS AND USES THEREOF

Publication Number WO/2020/109523
Publication Date 04.06.2020
International Application No. PCT/EP2019/083005
International Filing Date 28.11.2019
IPC
A61K 51/04 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
51Preparations containing radioactive substances for use in therapy or testing in vivo
02characterised by the carrier
04Organic compounds
A61P 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
CPC
A61K 51/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
51Preparations containing radioactive substances for use in therapy or testing in vivo
02characterised by the carrier ; , i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
04Organic compounds
A61K 51/0402
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
51Preparations containing radioactive substances for use in therapy or testing in vivo
02characterised by the carrier ; , i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
04Organic compounds
0402carboxylic acid carriers, fatty acids
A61K 51/0497
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
51Preparations containing radioactive substances for use in therapy or testing in vivo
02characterised by the carrier ; , i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
04Organic compounds
0497conjugates with a carrier being an organic compounds
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
Applicants
  • ITM ISOTOPEN TECHNOLOGIEN MÜNCHEN AG [DE]/[DE]
  • PAUL SCHERRER INSTITUT [CH]/[CH]
Inventors
  • BENESOVA, Martina
  • MÜLLER, Cristina
  • UMBRICHT, Christoph
  • SCHIBLI, Roger
  • ZHERNOSEKOV, Konstantin
  • DEBERLE, Luisa Maria
Agents
  • VON STOSCH, Andreas
  • LEHMBACHER, Michael
  • EICHELBAUM, Kornelia
  • SCHARPING, Marion
Priority Data
PCT/EP2018/08291028.11.2018EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) NOVEL TUMOR ANTIGEN BINDING AGENTS AND USES THEREOF
(FR) NOUVEAUX AGENTS DE LIAISON À L'ANTIGÈNE TUMORAL ET LEURS UTILISATIONS
Abstract
(EN)
The present invention provides compounds according to General Formula (1 )(i) or (1 )(ii): wherein A is a diagnostic or therapeutic agent comprising a binding site for a tumor antigen, and the spacer comprises at least one C-N bond.
(FR)
La présente invention concerne des composés selon la formule générale (1)(i) ou (1)(ii) : dans laquelle A est un agent thérapeutique ou de diagnostic comprenant un site de liaison pour un antigène tumoral, et l'espaceur comprend au moins une liaison C-N.
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