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1. WO2020109504 - USE OF OLIGODENDROCYTES FROM ORAL NEUROECTODERMAL STEM CELLS IN THE REPAIR OF THE NERVOUS SYSTEM

Publication Number WO/2020/109504
Publication Date 04.06.2020
International Application No. PCT/EP2019/082967
International Filing Date 28.11.2019
IPC
C12N 5/079 2010.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07Animal cells or tissues
071Vertebrate cells or tissues, e.g. human cells or tissues
079Neural cells
A61K 35/30 2015.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
30Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
CPC
A61K 35/30
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
30Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
C12N 2506/097
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2506Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
09from epidermal cells, from skin cells, from oral mucosa cells
097from oral mucosa cells
C12N 5/0622
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor;
06Animal cells or tissues; Human cells or tissues
0602Vertebrate cells
0618Cells of the nervous system
0622Glial cells, e.g. astrocytes, oligodendrocytes; Schwann cells
Applicants
  • ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS [FR]/[FR]
  • UNIVERSITÉ DE PARIS 5 RENÉ DESCARTES [FR]/[FR]
  • UNIVERSITÉ PARIS DIDEROT-PARIS 7 [FR]/[FR]
  • UNIVERSITÉ PARIS EST CRÉTEIL VAL DE MARNE [FR]/[FR]
Inventors
  • FOURNIER, Benjamin
  • GOGLY, Bruno
  • MARCHAND-LEROUX, Catherine
  • NASSIF, Ali
  • TAÏHI, Ihsène
Priority Data
18306590.330.11.2018EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) USE OF OLIGODENDROCYTES FROM ORAL NEUROECTODERMAL STEM CELLS IN THE REPAIR OF THE NERVOUS SYSTEM
(FR) UTILISATION D'OLIGODENDROCYTES À PARTIR DE CELLULES SOUCHES NEUROECTODERMIQUES ORALES DANS LA RÉPARATION DU SYSTÈME NERVEUX
Abstract
(EN)
This invention concerns a new method for differentiating oral neuroectodermal stem cells (CSO-NE), in particular human gingival neuroectodermal stem cells (CSGh), into oligodendrocytes (OL), and their use in the repair of the nervous system, in particular of head injuries.
(FR)
Nouveau procédé de différenciation de cellules souches neuroectodermiques orales (CSO-NE), en particulier des cellules souches neuroectodermiques gingivales humaines (CSGh), en oligodendrocytes (OL), et leur utilisation dans la réparation du système nerveux, en particulier lors de blessures de la tête.
Also published as
Latest bibliographic data on file with the International Bureau