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1. WO2020109388 - WELLS FOR OPTIMIZED SAMPLE LOADING IN MICROFLUIDIC CHIPS

Publication Number WO/2020/109388
Publication Date 04.06.2020
International Application No. PCT/EP2019/082748
International Filing Date 27.11.2019
IPC
B01L 3/00 2006.01
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
CPC
B01L 2200/0642
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2200Solutions for specific problems relating to chemical or physical laboratory apparatus
06Fluid handling related problems
0642Filling fluids into wells by specific techniques
B01L 2200/0673
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2200Solutions for specific problems relating to chemical or physical laboratory apparatus
06Fluid handling related problems
0673Handling of plugs of fluid surrounded by immiscible fluid
B01L 2200/0684
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2200Solutions for specific problems relating to chemical or physical laboratory apparatus
06Fluid handling related problems
0684Venting, avoiding backpressure, avoid gas bubbles
B01L 2300/0829
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2300Additional constructional details
08Geometry, shape and general structure
0809rectangular shaped
0829Multi-well plates; Microtitration plates
B01L 2300/0851
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2300Additional constructional details
08Geometry, shape and general structure
0848Specific forms of parts of containers
0851Bottom walls
B01L 2400/0688
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2400Moving or stopping fluids
06Valves, specific forms thereof
0688surface tension valves, capillary stop, capillary break
Applicants
  • STILLA TECHNOLOGIES [FR]/[FR]
Inventors
  • FERNANDEZ, Nicolas
  • FRADET, Étienne
  • DANGLA, Rémi
Agents
  • ICOSA
Priority Data
19305420.229.03.2019EP
19305421.029.03.2019EP
62/771,78427.11.2018US
62/771,91627.11.2018US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) WELLS FOR OPTIMIZED SAMPLE LOADING IN MICROFLUIDIC CHIPS
(FR) PUITS POUR CHARGEMENT D'ÉCHANTILLON OPTIMISÉ DANS DES PUCES MICROFLUIDIQUES
Abstract
(EN)
The present invention relates to a loading well (320) comprising a lateral wall part (3211) in cross-section parallel to the base plan (x/y) and/or a bottom wall part comprising at least one sloped bottom section (32121). The present invention also relates to a microfluidic chip comprising the same; systems comprising the same configured to reduce the dead volume of a drop of sample to be loaded in the microfluidic chip and/or to trap a drop in a defined location; and methods using the same.
(FR)
La présente invention concerne un puits de chargement (320) comprenant une partie de paroi latérale (3211) en section transversale parallèle au plan de base (x/y) et/ou une partie de paroi inférieure comprenant au moins une section inférieure inclinée (32121). La présente invention concerne également une puce microfluidique le comprenant; des systèmes comprenant ceux-ci configurés pour réduire le volume mort d'une goutte d'échantillon à charger dans la puce microfluidique et/ou pour piéger une goutte dans un emplacement défini; et des procédés l'utilisant.
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