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1. WO2020108781 - IMMOBILISATION OF RECEPTOR MOLECULES ON SURFACES BY TETRAZINE LIGATION

Publication Number WO/2020/108781
Publication Date 04.06.2020
International Application No. PCT/EP2018/083217
International Filing Date 30.11.2018
IPC
G01N 33/543 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
543with an insoluble carrier for immobilising immunochemicals
B01D 67/00 2006.01
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
DSEPARATION
67Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
B01D 69/10 2006.01
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
DSEPARATION
69Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
10Supported membranes; Membrane supports
B01D 69/12 2006.01
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
DSEPARATION
69Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
12Composite membranes; Ultra-thin membranes
CPC
B01D 2323/30
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
DSEPARATION
2323Details relating to membrane preparation
30Cross-linking
B01D 2323/34
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
DSEPARATION
2323Details relating to membrane preparation
34Use of radiation
B01D 2323/36
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
DSEPARATION
2323Details relating to membrane preparation
36Introduction of specific chemical groups
B01D 67/0006
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
DSEPARATION
67Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
0002Organic membrane formation
0006by chemical reactions
B01D 67/0093
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
DSEPARATION
67Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
0081After-treatment of organic or inorganic membranes
0093Chemical modification
B01D 69/12
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
DSEPARATION
69Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
12Composite membranes; Ultra-thin membranes
Applicants
  • CNM TECHNOLOGIES GMBH [DE]/[DE]
  • APTARION BIOTECH [DE]/[DE]
Inventors
  • SCHNIEDERS, Albert
  • MEYERBRÖKER, Nikolaus
  • VATER, Axel
Agents
  • TEGETHOFF, Sebastian
Priority Data
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) IMMOBILISATION OF RECEPTOR MOLECULES ON SURFACES BY TETRAZINE LIGATION
(FR) IMMOBILISATION DE MOLÉCULES RÉCEPTRICES SUR DES SURFACES PAR LIGATURE DE TÉTRAZINE
Abstract
(EN)
The present invention relates to the immobilisation of receptor molecules like nucleic acids or other biomolecules on surfaces which are suitable amongst other purposes for biosensors. The invention provides a method and use of CNMs which are terminated with tetrazine ligation active groups (TeLAGs) that may be functionalised by coupling of receptors or oligonucleotides.
(FR)
La présente invention concerne l'immobilisation d'acides nucléiques de type molécules réceptrices ou d'autres biomolécules sur des surfaces qui sont appropriées entre autres fins à des biocapteurs. L'invention concerne un procédé et l'utilisation de nanomembranes carbonées (CNM) qui ont une terminaison avec des groupes actifs à ligature tétrazine (ZeLAG) qui peuvent être fonctionnalisées par couplage de récepteurs ou d'oligonucléotides.
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